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NCT06091553
Comparison of the Efficacy and Safety of Duloxetine Augmented With Gabapentin and Duloxetine Augmented With Amitriptyline vs Duloxetine Alone in Chemotherapy -Induced Neuropathy
Phase 2 trial testing Duloxetine alone in Neuropathy in Cacer Patien in 160 participants. Currently enrolling.
30 September 2024
Quick facts
| Lead sponsor | Beni-Suef University |
|---|---|
| Phase | Phase 2 |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 160 |
| Start date | 10 October 2023 |
| Primary completion | 30 September 2024 |
| Estimated completion | 31 December 2024 |
| Sites | 1 location across Egypt |
Drugs / interventions tested
- Duloxetine alone — full drug profile →
- Duloxetine augmented with gabapentin — full drug profile →
- Duloxetine augmented with amitriptyline (as combined therapy) — full drug profile →
Conditions studied
- Neuropathy in Cacer Patien — all drugs for Neuropathy in Cacer Patien →
Sponsor
Beni-Suef University
Who can join
Adults 18 to 75, any sex, with Neuropathy in Cacer Patien. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study aimed to elucidate the relationship between the Efficacy and Safety of Comparison of the Efficacy and Safety Duloxetine augmented with gabapentin and amitriptyline augmented with Duloxetine vs duloxetine alone in chemotherapy -Induced Neuropathy in cancer patients.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Efficacy and Safety of Duloxetine with Gabapentin or Amitriptyline Versus Duloxetine Monotherapy in Chemotherapy-Induced Peripheral Neuropathy: Randomized Controlled Trial.
Salah H, Shaaban AH, Abdelrahman MA, Osama H, et al · · 2026 · PMID 42075808 · DOI 10.3390/ph19040553
Verify or expand the search:
- PubMed search for NCT06091553
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06091553 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Beni-Suef University
- Last refreshed: 16 April 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06091553.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing