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NCT06073899
Biopsychosocial Factors in Resistance Exercise in Individuals with Knee Pain
NA trial testing Leg Extension Exercise in Knee Pain in 57 participants. Completed in 20 September 2024.
20 September 2024
Quick facts
| Lead sponsor | University of Central Florida |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | crossover |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 57 |
| Start date | 16 January 2024 |
| Primary completion | 20 September 2024 |
| Estimated completion | 20 September 2024 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Leg Extension Exercise
Conditions studied
- Knee Pain — all drugs for Knee Pain →
Sponsor
University of Central Florida
Who can join
Adults 18 to 60, any sex, with Knee Pain. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The purpose of this research is to examine changes in pain sensitivity during high fatigue exercise, low fatigue exercise, and no treatment in individuals who are currently experiencing knee pain. Dosing dynamic resistance exercise intensity based on fatigue level is a novel, clinically feasible method. Dynamic resistance exercise at a high intensity (75% 1 repetition maximum (RM)) produces significant hypoalgesia at local sites compared to no treatment; however, dosing intensity based on 1RM can be challenging to implement in the clinical setting. Fatiguing endurance tasks produce local and systemic reductions in pressure pain threshold with low intensity isometric exercise completed until failure resulting in the largest exercise induced hypoalgesia effects. Fatigue may be an important mediator in pain response to exercise.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT06073899
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
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- Google Scholar
Related trials
Other recruiting trials for Knee Pain
Currently open trials in the same condition.
- NCT07158736 — Genicular Nerve Block for Knee Pain in the ED · NA · recruiting
Other University of Central Florida trials
Trials by the same sponsor.
- NCT07203430 — Biopsychosocial Factors and Muscle Morphology After a Resistance Exercise · NA · completed
- NCT07214883 — UCF MammoChat: Image Repository · recruiting
- NCT06999057 — Quadriceps Motor Unit Adaptation to Simulated Knee Injury · NA · not yet recruiting
- NCT06979713 — Yoga, Education, and Nidra (YEN) for Chronic Low Back Pain: A Pilot Study on Pain Modulation, Well-Being, and Sleep · NA · not yet recruiting
- NCT06512168 — Measuring Aided Language Development · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06073899 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Central Florida
- Last refreshed: 26 September 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06073899.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing