Last reviewed · How we verify
NCT06073145: TCD
Transcranial Doppler Using Wearable Ultrasound Patch
trial testing conventional transcranial Doppler probe and wearable ultrasound patch. in Medical Device Complication in 36 participants. Completed in 8 April 2024.
2 April 2024
Quick facts
| Lead sponsor | University of California, San Diego |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 36 |
| Start date | 27 September 2022 |
| Primary completion | 2 April 2024 |
| Estimated completion | 8 April 2024 |
| Sites | 1 location across United States |
Drugs / interventions tested
- conventional transcranial Doppler probe and wearable ultrasound patch.
Conditions studied
- Medical Device Complication — all drugs for Medical Device Complication →
- Brain Injuries — all drugs for Brain Injuries →
- Brain Diseases — all drugs for Brain Diseases →
- Stroke — all drugs for Stroke →
Sponsor
University of California, San Diego
Who can join
18 and older, any sex, with Medical Device Complication or Brain Injuries. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The main objective of this research is to measure the Doppler signal by the ultrasonic patch. Blood flow measurement is critical for vasospasm, stroke, and embolism monitoring on patients in the ICU or understanding the neurovascular coupling on different subjects. Currently, A conventional transcranial Doppler (TCD) probe is widely used for these applications. A headset design must be applied and fixed on the participants to obtain stable blood flow spectra. However, the TCD headset is operator dependent. The operator needs to be a trained expert and hold the ultrasound probe to get accurate blood flow velocity information. The stretchable and wearable non-invasive ultrasonic patch can not only free the operator's hands but can also provide long-term continuous monitoring, which is not possible by using the current operator-dependent ultrasound machine. The device can be conformal to the skin and attached to the skin surface.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Transcranial volumetric imaging using a conformal ultrasound patch.
Zhou S, Gao X, Park G, Yang X, et al · · 2024 · cited 64× · PMID 38778234 · DOI 10.1038/s41586-024-07381-5
Verify or expand the search:
- PubMed search for NCT06073145
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06073145 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of California, San Diego
- Last refreshed: 10 April 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06073145.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing