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NCT06066593

Prediction Model for Chronic Intracranial Arterial Occlusion With Radiomic Features

Status unknown Last updated 4 October 2023
What this trial tests

trial in Stroke, Ischemic in 1,000 participants. Status unknown.

Timeline
1 August 2023
Primary endpoint
1 August 2024
31 December 2024

Quick facts

Lead sponsorBeijing Hospital
StatusStatus unknown
Study typeOBSERVATIONAL
Enrollment1,000
Start date1 August 2023
Primary completion1 August 2024
Estimated completion31 December 2024
Sites2 locations across China

Conditions studied

Sponsor

Beijing Hospital

Who can join

Adults 18 to 80, any sex, with Stroke, Ischemic or Stroke Hemorrhagic. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Chronic intracranial arterial occlusion is associated with a "bidirectional stroke risk," with a significantly increased risk of both ischemic stroke and cerebral hemorrhage. Currently, Western CTAP products, in combination with clinical expertise, offer some predictive value for assessing the risk of ischemic events by evaluating compensatory pathways and overall perfusion in chronic intracranial arterial occlusion. However, there is limited support for assessing the risk of hemorrhagic events. Our proposed project aims to address a significant scientific challenge: the precise assessment of long-term stroke risk in asymptomatic patients with chronic intracranial arterial occlusion using a machine learning-based approach. The rapidly advancing field of machine learning provides a rich set of solutions for tackling this problem. In this project, we intend to develop a deep learning-based segmentation model for key brain regions using multimodal CT scans. Subsequently, we will automate the extraction of radiomic features and CT perfusion parameters, followed by the application of machine learning techniques to construct a stroke risk prediction model tailored for patients with chronic intracranial arterial occlusion.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

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Other recruiting trials for Stroke, Ischemic

Currently open trials in the same condition.

Other Beijing Hospital trials

Trials by the same sponsor.

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Data sources for this page

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