Last reviewed · How we verify
NCT06065943: PARFEM
Ultrasound-guided In-plane Puncture of the Femoral Artery
NA trial testing Palpation and Fluoroscopy in Vessel Puncture Site Bleeding in 286 participants. Completed in 30 June 2024.
31 March 2024
Quick facts
| Lead sponsor | Wuerzburg University Hospital |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | diagnostic |
| Enrollment | 286 |
| Start date | 1 July 2022 |
| Primary completion | 31 March 2024 |
| Estimated completion | 30 June 2024 |
| Sites | 1 location across Germany |
Drugs / interventions tested
- Palpation and Fluoroscopy
- Ultrasound guidance
Conditions studied
- Vessel Puncture Site Bleeding — all drugs for Vessel Puncture Site Bleeding →
Sponsor
Wuerzburg University Hospital
Who can join
Eligibility, any sex, with Vessel Puncture Site Bleeding. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
In Germany almost 1 million cardiac catheterizations are performed each year. These procedures can be done either by a transradial or a transfemoral approach. Today, the transradial approach is the recommended default strategy. Nevertheless, transfemoral access ist still frequently used. The main draw-back of a transfemoral approach are potential access site complications, which can sometimes be life-threatening. To reduce vascular complications ultrasound guided vessel puncture may be helpful. In the "Ultrasound guided puncture of the femoral artery"-Study (US-Parfem) an optimized method of ultrasound guided femoral puncture will be evaluated. In this randomized study the new puncture technique combining ultrasound and fluoroscopy will be compared with the conventional method guided by vessel palpation and fluoroscopy. Primary endpoint of the study is the rate of primary successful puncture of the femoral common artery above the bifurcation and below the inguinal ligament ("first success rate").
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Can Ultrasound-Guided in-Plane Puncture Technique Enhance the Precision of Femoral Artery Access? The Randomized PARFEM Trial.
Voelker W, Lachmann M, Gueder G, Bayik A, et al · · 2025 · PMID 40735901 · DOI 10.1002/ccd.31733
Verify or expand the search:
- PubMed search for NCT06065943
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06065943 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Wuerzburg University Hospital
- Last refreshed: 15 August 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06065943.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing