Who is sponsoring NCT06065163?

NCT06065163 is sponsored by Instituto Nacional de Cardiologia Ignacio Chavez.

What drugs are being tested in NCT06065163?

Interventions in NCT06065163: Diuretic de/escalation based on ultrasound findings (VExUS Score), Diuretic de/escalation based on clinical findings (CCS Score).

What condition does NCT06065163 study?

NCT06065163 studies Cardiorenal Syndrome Type 1.

Is NCT06065163 still recruiting?

NCT06065163 is currently status unknown. Last updated 5 October 2023.

Last reviewed 2023-10-05 · How we verify

NCT06065163: NEEDED

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Ultrasound Guided Diuretic Therapy in Type 1 Cardiorenal Syndrome

Status unknown NA Last updated 5 October 2023

What this trial tests

NA trial testing Diuretic de/escalation based on ultrasound findings (VExUS Score) in Cardiorenal Syndrome Type 1 in 80 participants. Status unknown.

Timeline

1 September 2022

Primary endpoint
31 December 2024

31 March 2025

Quick facts

Lead sponsor	Instituto Nacional de Cardiologia Ignacio Chavez
Phase	NA
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	randomized
Design	factorial
Masking	double
Primary purpose	treatment
Enrollment	80
Start date	1 September 2022
Primary completion	31 December 2024
Estimated completion	31 March 2025
Sites	1 location across Mexico

Drugs / interventions tested

Diuretic de/escalation based on ultrasound findings (VExUS Score)
Diuretic de/escalation based on clinical findings (CCS Score)

Conditions studied

Cardiorenal Syndrome Type 1 — all drugs for Cardiorenal Syndrome Type 1 →

Sponsor

Instituto Nacional de Cardiologia Ignacio Chavez — full company profile →

Who can join

Eligibility, any sex, with Cardiorenal Syndrome Type 1. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

A double-blind, randomized, controlled trial was conducted with the main objective of evaluating if patients with clinical assessment and VExUS reach decongestion faster within a maximum period of 7 days during the hospital stay. Likewise, the study will describe those patients who experience a decrease in serum creatinine (CrS), NT-proBNP at discharge, greater diuretic adjustment, rate of intrahospital readmission, and 30-day mortality.

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

Point-of-Care Ultrasound in Nephrology: Beyond Kidney Ultrasound.
Gómez-Johnson VH, López-Gil S, Argaiz ER, Koratala A. · · 2025 · cited 4× · PMID 39941227 · DOI 10.3390/diagnostics15030297
A Pragmatic Approach to Acute Cardiorenal Syndrome: Diagnostic Strategies and Targeted Therapies to Overcome Diuretic Resistance.
Tran P, Khweir L, Kuehl M, Joshi M, et al · · 2025 · cited 2× · PMID 40364029 · DOI 10.3390/jcm14092996
Venous Excess Ultrasound Score and Acute Kidney Injury in Patients With Acute Heart Failure.
Araiza-Garaygordobil D, Gonzalez-Macedo E, Argaiz E, Ezquerra-Osorio A, et al · · 2026 · PMID 42206794 · DOI 10.1016/j.jacadv.2026.102752

Verify or expand the search:

Other Instituto Nacional de Cardiologia Ignacio Chavez trials

Trials by the same sponsor.

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NCT06013813 — Conventional vs. Distal Radial Access Outcomes in STEMI Patients Treated by PCI · NA · unknown

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT06065163 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Instituto Nacional de Cardiologia Ignacio Chavez
Last refreshed: 5 October 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06065163.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing