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NCT06062264

Patient Portal Flu Vaccine Reminders (RCT 6)

Completed NA Results posted Last updated 20 April 2025
What this trial tests

NA trial testing Portal-based Video Message in Influenza in 22,233 participants. Completed in 1 April 2024.

Timeline
3 October 2023
Primary endpoint
1 April 2024
1 April 2024

Quick facts

Lead sponsorUniversity of California, Los Angeles
PhaseNA
StatusCompleted
Study typeINTERVENTIONAL
Allocationrandomized
Designparallel
Maskingsingle
Primary purposehealth services research
Enrollment22,233
Start date3 October 2023
Primary completion1 April 2024
Estimated completion1 April 2024
Sites1 location across United States

Drugs / interventions tested

Conditions studied

Sponsor

University of California, Los Angeles

Who can join

6 Months and older, any sex, with Influenza or Respiratory Tract Infections. Patients with the condition only — healthy volunteers not accepted.

Results — posted to ClinicalTrials.gov

Per-arm endpoint measurements with 95% confidence intervals where reported. Source: trial results section.

Receipt of the Annual Influenza Vaccine Among Index Patients Primary · 6 months

Percent of patients with annual influenza vaccination (between 10/4/23 - 4/1/24) among adult patients. Outcomes will be assessed via vaccine data extraction from the electronic health record and external claims and pharmacy data. The index patients must also be an active UCLA Health MyChart user (\>= 1 login over the last 12 months from 8/1/23, excluding activity on the user's initial profile activation date). Individuals not affiliated with any primary care practice will be excluded from the primary analysis.

GroupValue95% CI
Portal-Based PCP Video Reminder Message3557
Portal-Based PCP Infographic Reminder Message3518
Standard Health System Portal Messages3479
Receipt of the Annual Influenza Vaccine Among Pediatric Index Patients Secondary · 6 months

Percent of patients with annual influenza vaccination (between 10/4/23 - 4/1/24) among pediatric index patients. Outcomes will be assessed via vaccine data extraction from the electronic health record and external claims and pharmacy data. The index patients must also be an active UCLA Health MyChart user (\>= 1 login over the last 12 months from 8/1/23, excluding activity on the user's initial profile activation date). Individuals not affiliated with any primary care practice will be excluded from the primary analysis.

GroupValue95% CI
Portal-Based PCP Video Reminder Message618
Portal-Based PCP Infographic Reminder Message598
Standard Health System Portal Messages576

Sponsor's own description

This trial is taking place in Los Angeles, CA at 21 clinics within the UCLA Health System. The study design is a 3 arm randomized trial. Patients will be randomized into 1) receiving portal based reminder messages with a video from their PCP encouraging them to receive the influenza vaccine, 2) portal-based reminder messages with an infographic with the image of their PCP encouraging them to receive the influenza vaccine, or 3) the control group. Patients randomized to the intervention arms will receive reminders if they are due for influenza vaccine. Despite the Advisory Committee on Immunization Practices (ACIP) recommendation in 2010 that all people above 6 months of age should receive an annual flu vaccine, vaccination rates remain low: at 6m-4.9 yrs. (70%), 5-17.9 yrs. (56%), 18-64.9 yrs. (38%), and \>65 yrs. (63%). The investigators will assess the effectiveness of MyChart R/R video messages and infographic messages as compared to the standard of care control (Health system messages).

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. Video and Infographic Messages From Primary Care Physicians and Influenza Vaccination Rates: A Randomized Clinical Trial.
    Szilagyi PG, Clark EJ, Duru OK, Casillas A, et al · · 2025 · cited 1× · PMID 40802184 · DOI 10.1001/jamanetworkopen.2025.26514

Verify or expand the search:

Other recruiting trials for Influenza

Currently open trials in the same condition.

Other University of California, Los Angeles trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06062264.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing