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NCT06057103: ZX-7101A-208
A Study to Evaluate Drug-drug Interaction of ZX-7101A Tablets and Oseltamivir Phosphate Capsules in Healthy Adult Subjects
Phase 1 trial testing ZX-7101A in Drug Interaction in 18 participants. Completed in 26 April 2024.
5 December 2023
Quick facts
| Lead sponsor | Nanjing Zenshine Pharmaceuticals |
|---|---|
| Phase | Phase 1 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | non randomized |
| Design | crossover |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 18 |
| Start date | 28 August 2023 |
| Primary completion | 5 December 2023 |
| Estimated completion | 26 April 2024 |
| Sites | 1 location across China |
Drugs / interventions tested
- ZX-7101A — full drug profile →
- Oseltamivir — full drug profile →
- ZX-7101A and Oseltamivir — full drug profile →
- ZX-7101A — full drug profile →
- Oseltamivir — full drug profile →
- ZX-7101A and Oseltamivir — full drug profile →
- ZX-7101A — full drug profile →
Conditions studied
- Drug Interaction — all drugs for Drug Interaction →
Sponsor
Nanjing Zenshine Pharmaceuticals — full company profile →
Who can join
Adults 18 to 45, any sex, with Drug Interaction. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The primary object of this study is evaluating the effect of multiple oral oseltamivir phosphate capsules on the pharmacokinetic profile of the active metabolite ZX-7101 after a single oral administration of ZX-7101A tablet in healthy Chinese adult subjects. The seongdary object is evaluating combined or uncombined multiple oral oseltamivir phosphate in healthy Chinese adult subjects.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT06057103
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of ZX-7101A
Trials testing the same drug.
- NCT06669351 — Study to Assess the Safety and Efficacy of ZX-7101A in Children Aged 5-11 Years With Influenza · Phase 3 · terminated
- NCT06099873 — Study to Assess the Safety and Efficacy of ZX-7101A in Adolescents With Influenza · Phase 3 · completed
- NCT05955027 — A Study to Evaluate the Effect of a Single Oral Dose of ZX-7101A on the QTc Interval in Healthy Subjects · Phase 1 · completed
- NCT05949385 — A Study to Assess the Effect of Itraconazole Capsules on the Pharmacokinetics of ZX-7101A Tablets in Healthy Adult Subje · Phase 1 · completed
- NCT05702489 — A Study to Evaluate the Efficacy and Safety of ZX-7101A Tablets in Adults with Uncomplicated Influenza · Phase 2, PHASE3 · completed
Other recruiting trials for Drug Interaction
Currently open trials in the same condition.
- NCT06717581 — Variation in Drug Interactions in People With HIV (PLWH) Aged 60 Years and Older. · recruiting
- NCT05512169 — Pharmacogenomic Association Study in Indian Children With Acute Lymphoblastic Leukemia · recruiting
- NCT04593680 — Assessment of Drug-drug Interactions Between Masculinizing Hormone Therapy and Antiretroviral Agents Concomitantly for P · NA · active not recruiting
- NCT04590417 — Assessment of Drug-drug Interactions Between Feminizing Hormone Therapy and Emtricitabine/Tenofovir Alafenamide Concomit · NA · active not recruiting
Other Nanjing Zenshine Pharmaceuticals trials
Trials by the same sponsor.
- NCT07310134 — Study to Evaluate Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Efficacy of ZX-8177 in Patients With Adva · Phase 1 · recruiting
- NCT07095257 — Study to Assess the Safety and Efficacy of ZX-7101A for Oral Suspension in Chinese Pediatric Participants 2 to 11 Years · Phase 3 · completed
- NCT06841926 — Study to Evaluate the Pharmacokinetics and Relative Bioavailability of Metabolites in Healthy Chinese Adult Males · Phase 1 · completed
- NCT06669351 — Study to Assess the Safety and Efficacy of ZX-7101A in Children Aged 5-11 Years With Influenza · Phase 3 · terminated
- NCT06099873 — Study to Assess the Safety and Efficacy of ZX-7101A in Adolescents With Influenza · Phase 3 · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06057103 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Nanjing Zenshine Pharmaceuticals
- Last refreshed: 4 November 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06057103.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing