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NCT06056089: MODAM-MAM
Modified Dosage for Moderate Acute Malnutrition (MODAM-MAM)
NA trial testing ready-to-use supplementary food (RUSF) in Moderate Acute Malnutrition in 2,400 participants. Currently enrolling.
25 September 2026
Quick facts
| Lead sponsor | Action Against Hunger USA |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | treatment |
| Enrollment | 2,400 |
| Start date | 25 September 2023 |
| Primary completion | 25 September 2026 |
| Estimated completion | 25 September 2026 |
| Sites | 3 locations across Ethiopia |
Drugs / interventions tested
- ready-to-use supplementary food (RUSF)
- ready-to-use therapeutic food (RUTF)
Conditions studied
- Moderate Acute Malnutrition — all drugs for Moderate Acute Malnutrition →
Sponsor
Action Against Hunger USA
Who can join
Adults 6 Months to 59 Months, any sex, with Moderate Acute Malnutrition. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Protocols for the community-based management of acute malnutrition (CMAM) have not changed significantly for more than 20 years, with relatively complex treatment protocols and persistent supply chain challenges that have limited overall program coverage, leaving millions of malnourished children without care annually. The overarching goal of this research project is to simultaneously test two novel simplified approaches in CMAM with potential to improve program coverage. The simplified approach includes two parallel clinical trials for SAM and MAM treatment. Two fixed-dose regimes of RUTF will be tested against the current fixed-dose regimen of RUSF for children with MAM.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
The Modified Dosages for Acute Malnutrition (MODAM) study: protocol for three integrated randomized controlled trials of novel approaches for the management of childhood wasting in Ethiopia.
Trehan I, Beyene Y, Darsene H, Adams BS, et al · · 2025 · cited 2× · PMID 40200326 · DOI 10.1186/s40795-025-01054-w
Verify or expand the search:
- PubMed search for NCT06056089
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Moderate Acute Malnutrition
Currently open trials in the same condition.
- NCT06038071 — Family Mid-Upper Arm Circumference (MUAC) Follow-up After Recovery From Acute Malnutrition (MODAM-fMUAC) · NA · recruiting
Other Action Against Hunger USA trials
Trials by the same sponsor.
- NCT06038071 — Family Mid-Upper Arm Circumference (MUAC) Follow-up After Recovery From Acute Malnutrition (MODAM-fMUAC) · NA · recruiting
- NCT06061484 — Modified Dosage for Severe Acute Malnutrition · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06056089 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Action Against Hunger USA
- Last refreshed: 16 July 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06056089.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing