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MRI Guided Closed-loop TMS-EEG
The goal of this interventional study is to develop an individualized approach using transcranial magnetic stimulation (TMS) in a high-precision manner. This approach will use TMS to modulate brain activity at multiple locations simultaneously. Functional magnetic resonance imaging (fMRI) and electroencephalograph (EEG) will record the responses and guide the stimulation. Specifically, the placement and orientation of TMS coils will be tailored to stimulate the targeted functional brain areas informed by fMRI. To maximize the interventional effect, stimulation pulses will be delivered based on EEG oscillations.
Details
| Lead sponsor | Sunnybrook Health Sciences Centre |
|---|---|
| Phase | NA |
| Status | RECRUITING |
| Enrolment | 160 |
| Start date | Thu Sep 07 2023 00:00:00 GMT+0000 (Coordinated Universal Time) |
| Completion | Sat Jul 31 2027 00:00:00 GMT+0000 (Coordinated Universal Time) |
Conditions
- Normal Physiology
- Amnestic Mild Cognitive Impairment
Interventions
- TMS
Countries
Canada