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NCT06047678
Acute Effect of Individual Variants of Agonist-antagonist and Traditional Agonistic Resistance Training on Cardiovascular Parameters
NA trial testing Cardiovascular fitness in Arterial Stiffness in 47 participants. Status unknown.
31 August 2023
Quick facts
| Lead sponsor | Charles University, Czech Republic |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | treatment |
| Enrollment | 47 |
| Start date | 1 April 2022 |
| Primary completion | 31 August 2023 |
| Estimated completion | 31 December 2024 |
| Sites | 2 locations across Czechia |
Drugs / interventions tested
- Cardiovascular fitness
Conditions studied
- Arterial Stiffness — all drugs for Arterial Stiffness →
- Hypertension — all drugs for Hypertension →
- Cardiovascular Diseases — all drugs for Cardiovascular Diseases →
Sponsor
Charles University, Czech Republic
Who can join
Adults 40 to 63, any sex, with Arterial Stiffness or Hypertension. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Prevention and non pharmacological treatment of prehypertension and hypertension stage 1 The effect of individual variants of agonist-antagonist and traditional agonistic resistance training on cardiovascular parameters in individuals with normotension and hypertension. What does the study involve? 1. Cardiovascular parameters 2. Body composition 3. Blood tests for heart disease 4. Training intervention A. Resistance training protocol: 75% 1RM, 10 reps, 3 sets, 2 min rest between sets and exercises, 16 exercises 1. Agonistic RT - upper body 2. Agonistic RT - lower body 3. Agonist-Antagonist - upper body 4. Agonist-Antagonist - lower body B. Aerobic training: 60% SF max, 4 x 10 min, 2 min rest between sets 5. Intraabdominal wall tension activity 6. The Borg rating of perceived exertion 7. Handgrip testing 8. Repetition testing (RM)
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Blood pressure changes during different methods of resistance training in normotensive and stage 1 hypertensive individuals: a repeated measures cross-sectional study.
Jurik R, Stastny P, Kolinger D, Gola A, et al · · 2025 · cited 3× · PMID 40087719 · DOI 10.1186/s13102-025-01097-3
Verify or expand the search:
- PubMed search for NCT06047678
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other Charles University, Czech Republic trials
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06047678 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Charles University, Czech Republic
- Last refreshed: 7 February 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06047678.
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