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NCT06046105
Efficacy of Adding Dexmedetomidine Versus Ibuprofen as an Adjuvant to Intraperitoneal Bupivacaine for Pain Control After Laparoscopic Gynecological Procedures
Phase 2, PHASE3 trial testing Administering intraperitoneal bupivacaine for pain control after laparoscopic gynecological procedures in Postoperative Pain, Acute in 180 participants. Status unknown.
1 March 2024
Quick facts
| Lead sponsor | Ain Shams University |
|---|---|
| Phase | Phase 2, PHASE3 |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | treatment |
| Enrollment | 180 |
| Start date | 15 September 2023 |
| Primary completion | 1 March 2024 |
| Estimated completion | 30 March 2024 |
Drugs / interventions tested
- Administering intraperitoneal bupivacaine for pain control after laparoscopic gynecological procedures
- Administering intraperitoneal bupivacaine plus Dexmedetomidine for pain control after laparoscopic gynecological procedures
- Administering intraperitoneal bupivacaine plus Ibuprofen for pain control after laparoscopic gynecological procedures
Conditions studied
- Postoperative Pain, Acute — all drugs for Postoperative Pain, Acute →
Sponsor
Ain Shams University
Who can join
Adults 18 to 60, female only, with Postoperative Pain, Acute. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The goal of this clinical trial is to compare the analgesic efficacy of adding dexmedetomidine versus ibuprofen to bupivacaine for intraperitoneal instillation after laparoscopic gynecological procedures. The main questions to answer are: * Which is more effective for controlling postoperative pain within the first 24 hours after the procedure? * Which is more convenient for the patients with fewer side effects and opioid consumption? Participants will be asked to assess * The postoperative pain severity by VAS score * The onset of the first analgesic request * The incidence of side effects like nausea and vomiting Researchers will compare the dexmedetomidine group, the ibuprofen group, and the bupivacaine (control) group to see which one will be superior to the others.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT06046105
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
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Other Ain Shams University trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06046105 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Ain Shams University
- Last refreshed: 21 September 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06046105.
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