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NCT06038513
Transnasal Induction of Normothermia for Neurogenic Fever
NA trial testing Transnasal Thermal Regulating Device in Stroke, Ischemic in 9 participants. Terminated before completion.
1 August 2025
Quick facts
| Lead sponsor | CoolTech LLC |
|---|---|
| Phase | NA |
| Status | Terminated |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 9 |
| Start date | 21 November 2023 |
| Primary completion | 1 August 2025 |
| Estimated completion | 30 November 2025 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Transnasal Thermal Regulating Device
Conditions studied
- Stroke, Ischemic — all drugs for Stroke, Ischemic →
- Stroke Hemorrhagic — all drugs for Stroke Hemorrhagic →
- Seizures — all drugs for Seizures →
- Metabolic Encephalopathy — all drugs for Metabolic Encephalopathy →
Sponsor
CoolTech LLC
Who can join
Adults 18 to 85, any sex, with Stroke, Ischemic or Stroke Hemorrhagic. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The objective of this study is to evaluate the efficacy of the COOLSTAT® Transnasal Thermal Regulating Device in reducing temperature in a population of febrile subjects who meet the inclusion/exclusion criteria.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT06038513
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Transnasal Thermal Regulating Device
Trials testing the same drug.
- NCT03360656 — Transnasal Induction of Normothermia in Febrile Stroke Patients · NA · completed
Other recruiting trials for Stroke, Ischemic
Currently open trials in the same condition.
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- NCT07135089 — Improving Neuroprotective Strategy for Ischemic Stroke Before Endovascular Thrombectomy by Intravenous Tirofiban · Phase 3 · recruiting
- NCT07047014 — Advancing Reperfusion Therapy for Ischemic Stroke (ARTS): Tenecteplase in Medium Vessel Occlusion (MeVO) for Acute Ische · Phase 3 · recruiting
Other CoolTech LLC trials
Trials by the same sponsor.
- NCT06051604 — Mi-Helper Transnasal Cooling for Acute Treatment of Migraine · NA · completed
- NCT04936061 — Transnasal Cooling for Migraine · NA · terminated
- NCT03360656 — Transnasal Induction of Normothermia in Febrile Stroke Patients · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06038513 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by CoolTech LLC
- Last refreshed: 26 January 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06038513.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing