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NCT06031064

External Validation of a Microscopic Colitis Clinical Scoring System in Patients With Chronic Watery Diarrhoea

Status unknown Last updated 11 September 2023
What this trial tests

trial in Microscopic Colitis in 200 participants. Status unknown.

Timeline
15 May 2022
Primary endpoint
1 February 2024
1 February 2024

Quick facts

Lead sponsorHospital Mutua de Terrassa
StatusStatus unknown
Study typeOBSERVATIONAL
Enrollment200
Start date15 May 2022
Primary completion1 February 2024
Estimated completion1 February 2024
Sites1 location across Spain

Conditions studied

Sponsor

Hospital Mutua de Terrassa

Who can join

40 and older, any sex, with Microscopic Colitis. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Chronic watery diarrhoea is a very common problem in the population and most of these patients will be referred for colonoscopy. If no macroscopic findings are observed during colonoscopy to justify the diarrhoea, serial colonic biopsies will be taken to rule out Microscopic Colitis (MC). However, it has been estimated that only 10-15% of these patients will be diagnosed with MC after colonoscopy. Therefore, about 80% of the biopsies collected and analysed will not be useful to establish a diagnosis, considerably increasing costs. To predict the risk of developing MC, a new promising clinical scoring system has been recently developed. This score will be useful in the diagnostic work-up of chronic watery diarrhoea to prioritize colonoscopy with stepwise colonic biopsies in patients with a positive highly specific score for MC. In cases with a negative score, colonoscopy plus biopsies should be performed only if other diagnostic tests are negative. The aim of this current study is to externally validate the new scoring system to predict MC in patients with chronic watery diarrhoea.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

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Other recruiting trials for Microscopic Colitis

Currently open trials in the same condition.

Other Hospital Mutua de Terrassa trials

Trials by the same sponsor.

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Data sources for this page

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