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NCT06028789: AOSIS
AOrtic Surgery: Systemic Inflammatory Response Versus Sepsis
trial testing Blood sample test in Systemic Inflammatory Response Syndrome in 60 participants. Currently enrolling.
30 June 2024
Quick facts
| Lead sponsor | University Hospital Hradec Kralove |
|---|---|
| Status | Recruiting now |
| Study type | OBSERVATIONAL |
| Enrollment | 60 |
| Start date | 1 April 2022 |
| Primary completion | 30 June 2024 |
| Estimated completion | 30 June 2024 |
| Sites | 1 location across Czechia |
Drugs / interventions tested
- Blood sample test
- Thoracic Aortic Surgery
Conditions studied
- Systemic Inflammatory Response Syndrome — all drugs for Systemic Inflammatory Response Syndrome →
- Infections — all drugs for Infections →
- Thoracic Aortic Aneurysm — all drugs for Thoracic Aortic Aneurysm →
- Aortic Diseases — all drugs for Aortic Diseases →
Sponsor
University Hospital Hradec Kralove
Who can join
Adults 18 to 85, any sex, with Systemic Inflammatory Response Syndrome or Infections. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The goal of the prospective observational study is to evaluate the immunological background of inflammatory response often seen after open thoracic aortic surgery. Patients scheduled for this type of procedure will undergo a series of blood testing (preoperatively, and several times postoperatively). The blood samples will be used for a wide scale of immunological tests to better evaluate potential differential markers against infection. A control group will include patients with active infective endocarditis (preoperatively). The main question is if there is a biomarker able to determine a difference between sterile systemic inflammation and infection after thoracic aortic surgery. The second question is if there is a difference in dynamics of evaluated biomarkers between sterile postoperative inflammation and active endocarditis.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT06028789
- Europe PMC full search
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Other recruiting trials for Systemic Inflammatory Response Syndrome
Currently open trials in the same condition.
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Other University Hospital Hradec Kralove trials
Trials by the same sponsor.
- NCT07415655 — Modulation of Cerebral Ischemia by Albumin · Phase 2 · not yet recruiting
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06028789 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University Hospital Hradec Kralove
- Last refreshed: 21 May 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06028789.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing