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NCT06026033

The Effect of Anthropometrics on Desflurane Rise Time

Completed Last updated 22 December 2023
What this trial tests

trial testing Desflurane induction in Desflurane in 361 participants. Completed in 1 September 2023.

Timeline
1 February 2022
Primary endpoint
30 August 2023
1 September 2023

Quick facts

Lead sponsorRecep Tayyip Erdogan University
StatusCompleted
Study typeOBSERVATIONAL
Enrollment361
Start date1 February 2022
Primary completion30 August 2023
Estimated completion1 September 2023
Sites1 location across Turkey (Türkiye)

Drugs / interventions tested

Conditions studied

Sponsor

Recep Tayyip Erdogan University

Who can join

18 and older, any sex, with Desflurane or Anesthesia, General. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Desflurane is increasingly used in general anesthesia. Its pharmacokinetic properties are known and its distribution is easily modeled. Yet these models fail in practice. In order to increase accuracy, any model should include cardiac output, alveolar ventilation and alveolar dead space, all of which are either hard to measure or impractical, at least. A previous study performed by the same investigator showed that time to target endtidal concentration of sevoflurane is prolonged with increased cardiac output, but only if the patient has increased muscle mass. Although desflurane has lower muscle and fat solubility, our observations suggest a similar prolongation in case of increased muscle mass. The investigators aim to investigate if patient characteristics such as gender, age, height, weight, body type prolongs time to reach target endtidal desflurane concentration in low flow anesthesia.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

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Other recruiting trials for Desflurane

Currently open trials in the same condition.

Other Recep Tayyip Erdogan University trials

Trials by the same sponsor.

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Data sources for this page

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