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NCT06025084
The Effect of the Egg Shell Nanoparticles Combined With Titanium Dioxide Nanoparticles
Phase 1 trial testing Egg Shell nanoparticles in Dentin Hypersensitivity in 24 participants. Completed in 30 March 2023.
15 March 2023
Quick facts
| Lead sponsor | Egymedicalpedia |
|---|---|
| Phase | Phase 1 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 24 |
| Start date | 1 December 2022 |
| Primary completion | 15 March 2023 |
| Estimated completion | 30 March 2023 |
| Sites | 1 location across Egypt |
Drugs / interventions tested
- Egg Shell nanoparticles — full drug profile →
Conditions studied
- Dentin Hypersensitivity — all drugs for Dentin Hypersensitivity →
Sponsor
Egymedicalpedia — full company profile →
Who can join
Adults 20 to 55, any sex, with Dentin Hypersensitivity. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Dentin hypersensitivity is one of the most commonly occurring clinical dental conditions which is characterized by short and sharp pain which arises from exposed dentin in response to external stimuli, which typically are thermal, evaporative, tactile, osmotic or chemical. Hypersensitive dentin is mostly found in buccal tooth areas, in which enamel is missing because of abrasion, attrition, or erosion. The most generally accepted theory regarding the mechanism of dentin hypersensitivity is the hydrodynamic theory. It proposes that a pain-provoking stimulus increases the flow of the dentinal tubular fluid and consequently, stimulates the nerves around the odontoblasts, leading to dentin hypersensitivity.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT06025084
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Dentin Hypersensitivity
Currently open trials in the same condition.
- NCT07431736 — Laser Therapy for Dentin Hypersensitivity · NA · active not recruiting
- NCT07069127 — Hydroxyapatite-Based Home Treatment for Dentin Sensitivity in Celiac Patients · NA · recruiting
- NCT07113847 — Effectiveness of Resin-Based Desensitizer and Laser, Compared to Fluoride Varnish in Management of Dentine Hypersensitiv · Phase 2, PHASE3 · active not recruiting
Other Egymedicalpedia trials
Trials by the same sponsor.
- NCT06590818 — The Effect of Body Mass Index on Short-term Results of HTO · NA · recruiting
- NCT06583811 — Remifentanil and Remimazolam to Limit Patient Movement · NA · recruiting
- NCT06522984 — Fractional Erbium YAG Laser vs Intradermal and Systemic Tranexamic Acid · NA · recruiting
- NCT06370078 — Effect of Early Administration of Albumin 20% Versus Crystalloid · NA · recruiting
- NCT06370221 — The Effect of Psoriatic Arthritis on Female Sexual Dysfunction · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06025084 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Egymedicalpedia
- Last refreshed: 6 September 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06025084.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing