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NCT06024759

Predictors of Risk in Left Ventricular Non-Compaction

Recruiting now Last updated 1 November 2023
What this trial tests

trial in Left Ventricular Noncompaction in 500 participants. Currently enrolling.

Timeline
1 September 2023
Primary endpoint
1 August 2033
1 August 2033

Quick facts

Lead sponsorLondon Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
StatusRecruiting now
Study typeOBSERVATIONAL
Enrollment500
Start date1 September 2023
Primary completion1 August 2033
Estimated completion1 August 2033
Sites1 location across Canada

Conditions studied

Sponsor

London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's

Who can join

18 and older, any sex, with Left Ventricular Noncompaction. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The goal of this study is to learn more about the risk factors associated with left ventricular non-compaction (LVNC) and the predictors of adverse outcomes associated with LVNC. The main questions this study aims to answer are as follows. * Are there any genetic mutations that impact the risk of LVNC patients developing ventricular arrhythmias? * Does LV myocardial strain increase risk stratification in the LVNC population with or without genetic mutations? * What are some of the determinants that cause LV dysfunction in LVNC? * What are other risk stratifiers (ex. premature ventricular contraction (PVC) burden on Holter, non-sustained ventricular tachycardia (NSVT) on stress test) that lead to an outcome of ICD implantation? Participants will have their medical records accessed annually for a span of ten years, either prospectively or retrospectively depending on whether they are being actively followed by physicians at the Inherited Arrhythmia Clinic or not, to evaluate LVNC progression over time. This data will be stored in a large clinical registry with the London Heart Rhythm Program at the London Health Sciences Centre, University Hospital Campus.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

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Other recruiting trials for Left Ventricular Noncompaction

Currently open trials in the same condition.

Other London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's trials

Trials by the same sponsor.

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Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06024759.

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