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The Importance of Prostaglandin and Nitric Oxide Synthesis in Apical Periodontitis

NCT06023901 NA COMPLETED

A total of 185 subjects were divided into three categories: AP group (n=85), CP group (n=50) and healthy control group (n=50). The AP group was divided into 3 subgroups according to abscess scoring (AS-PAI) based on the periapical index. The CP group was divided into 4 subgroups according to the periodontitis staging system (PSS). After recording the demographic and clinical characteristics of all participants, blood and gingival crevicular fluid (GCF) samples were taken. TNF-α, IL-10, PGE2 and NO levels were measured in these samples.

Details

Lead sponsorIstanbul Medipol University Hospital
PhaseNA
StatusCOMPLETED
Enrolment185
Start dateThu Jan 07 2021 00:00:00 GMT+0000 (Coordinated Universal Time)
CompletionWed Aug 02 2023 00:00:00 GMT+0000 (Coordinated Universal Time)

Conditions

Interventions

Countries

Turkey (Türkiye)