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Automitochondrial Transplantation Improves Live Birth in Elderly Patients With Low Prognosis After Repeated IVF Failure (ACTILB)
The goal to this clinical trial is to study the effectiveness and safety of automitochondrial transplantation of urine derived stem cells(USCs) in in elderly patients with low prognosis after repeated IVF failure. The main questions it aims to answer are: (1）test the effectiveness and safety of automitochondrial transplantation of urine derived stem cells (2) establish intracytoplasmic sperm injection(ICSI) mitochondrial transplantation platform Participants will be asked to:1)urine collections to further culture of autologous USCs 2)ovarian stimulation、trigger eggs、ICSI with autologous mitochondria 3）embryo transfer 4)accept pregnancy follow-up at given point
Details
| Lead sponsor | Peking University People's Hospital |
|---|---|
| Phase | NA |
| Status | UNKNOWN |
| Enrolment | 40 |
| Start date | Thu Feb 09 2023 00:00:00 GMT+0000 (Coordinated Universal Time) |
| Completion | Tue Dec 31 2024 00:00:00 GMT+0000 (Coordinated Universal Time) |
Conditions
- Infertility, Female
- Mitochondrial
- Elderly
- Assisted Reproductive Technique
Interventions
- Autologous USC mitochondrial oocyte transplantation
Countries
China