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Investigation of Fecal Microbiota Transplant in Chronic Intestinal Pseudo-obstruction Patients (FMT-CIP)
Chronic Intestinal Pseudo-Obstruction (CIPO) is a rare gastrointestinal disorder that primarily affects the movement of the intestines, leading to symptoms that resemble a true bowel obstruction but without a physical blockage. This condition is characterized by impaired motility of the gastrointestinal tract, which can result in severe symptoms and complications. In previous studies, the investigator found that sequential microbiota transplantation therapy can improve clinical symptoms of chronic pseudo-obstruction. Building on this foundation, the current study further investigates the effects of sequential interventions involving intestinal cleansing, small intestine bacterial treatment, fecal microbiota transplantation, and nutritional therapy on the short-term and long-term clinical symptom improvement in patients. Additionally, the investigator aim to elucidate the changes in gut microbiota phenotypes before and after treatment.
Details
| Lead sponsor | Shanghai 10th People's Hospital |
|---|---|
| Phase | NA |
| Status | COMPLETED |
| Enrolment | 10 |
| Start date | Mon Jan 01 2018 00:00:00 GMT+0000 (Coordinated Universal Time) |
| Completion | Tue Aug 01 2023 00:00:00 GMT+0000 (Coordinated Universal Time) |
Conditions
- Intestinal Pseudo-Obstruction
- Fecal Microbiota Transplantation
Interventions
- sequential fecal microbiota transplant combined with small intestinal fluid transplant
Countries
China