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NCT06019221: PRP

Pediatric Relapsing Polychondritis : Diagnosis and Management in a French Retrospective Study

Status unknown Last updated 2 November 2023
What this trial tests

trial in Relapsing Polychondritis in 20 participants. Status unknown.

Timeline
18 February 2023
Primary endpoint
18 January 2024
18 January 2024

Quick facts

Lead sponsorUniversity Hospital, Strasbourg, France
StatusStatus unknown
Study typeOBSERVATIONAL
Enrollment20
Start date18 February 2023
Primary completion18 January 2024
Estimated completion18 January 2024
Sites1 location across France

Conditions studied

Sponsor

University Hospital, Strasbourg, France

Who can join

Adults 1 to 17, any sex, with Relapsing Polychondritis. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The incidence in pediatrics is very low (about 3.5 per million per year according to a 2015 study) and therefore the data on the pathology very poor, especially on the therapeutic level. Without appropriate treatment, the disabling sequelae, even involving the vital prognosis, are significant. However, in paediatrics, therapeutic habits have been extrapolated from adult data and lack precision. Existing treatments are almost composed of immunomodulatory and/or immunosuppressive treatments. Different therapeutic lines have been introduced over the years and a better understanding of the pathology. More recently, biotherapies have been introduced in this pathology, but data on their effectiveness remain limited. Data on the evolution under therapy in children are thus still poor. Complications related to the pathology that can jeopardize the vital prognosis and the response to treatment for this pathology deserve to be studied in order to be known and if possible avoided. The aim of the study is to describe French practices and compare the lines of treatment proposed for juvenile atrophic polychondritis.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

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Other recruiting trials for Relapsing Polychondritis

Currently open trials in the same condition.

Other University Hospital, Strasbourg, France trials

Trials by the same sponsor.

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Data sources for this page

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