Last reviewed · How we verify
NCT06018090
Microembolic Detection in Acute Ischemic Stroke Patients With Atrial Fibrillation and Outcome
trial testing The presence and rate of MES measured by TCD monitoring in Infarction, Brain in 61 participants. Completed in 6 October 2022.
31 August 2022
Quick facts
| Lead sponsor | Centro Hospitalar De São João, E.P.E. |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 61 |
| Start date | 6 June 2019 |
| Primary completion | 31 August 2022 |
| Estimated completion | 6 October 2022 |
| Sites | 1 location across Portugal |
Drugs / interventions tested
- The presence and rate of MES measured by TCD monitoring
Conditions studied
- Infarction, Brain — all drugs for Infarction, Brain →
- Embolism — all drugs for Embolism →
- Atrial Fibrillation — all drugs for Atrial Fibrillation →
Sponsor
Centro Hospitalar De São João, E.P.E.
Who can join
18 and older, any sex, with Infarction, Brain or Embolism. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This multicenter international prospective cohort study will include patients with AIS with a known or newly diagnosed anticoagulant-naïve AF. All centers will use the same transcranial Doppler machine for one-hour monitoring with bilateral 2-MHz probes within 24 hours of symptom onset. Recordings will be analyzed for MES by a blinded central reader. The primary aim is to determine the proportion of patients with MES and the association of MES with functional outcomes assessed by a modified Rankin scale (mRS) score at 90 days.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Detection of microemboli in patients with acute ischaemic stroke and atrial fibrillation suggests poor functional outcome.
Castro P, Ferreira J, Malojcic B, Bazadona D, et al · · 2024 · cited 8× · PMID 38149620 · DOI 10.1177/23969873231220508
Verify or expand the search:
- PubMed search for NCT06018090
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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Currently open trials in the same condition.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06018090 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Centro Hospitalar De São João, E.P.E.
- Last refreshed: 30 August 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06018090.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing