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NCT06015672
Accelerated TMS for Focal Hand Dystonia
NA trial testing Transcranial Magnetic Stimulation (TMS) in Isolated Focal Hand Dystonia in 21 participants. Participants enrolled and being followed up; not accepting new ones.
5 February 2027
Quick facts
| Lead sponsor | Duke University |
|---|---|
| Phase | NA |
| Status | Active, enrolled |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | crossover |
| Masking | double |
| Primary purpose | treatment |
| Enrollment | 21 |
| Start date | 21 December 2023 |
| Primary completion | 5 February 2027 |
| Estimated completion | 5 February 2027 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Transcranial Magnetic Stimulation (TMS)
Conditions studied
- Isolated Focal Hand Dystonia — all drugs for Isolated Focal Hand Dystonia →
Sponsor
Duke University
Who can join
18 and older, any sex, with Isolated Focal Hand Dystonia. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study aims to investigate the impact of accelerated transcranial magnetic stimulation (TMS) on brain function and behavior in patients with focal hand dystonia. Previous research demonstrated that individualized TMS improved dystonic behavior after one session. Building on this, the current study administers four TMS sessions in a day, with assessments conducted in four weeks, twelve weeks, and 20 weeks after each session. The research involves 8 in-person and 6 virtual visits focused on functional MRI brain scans and writing behavior analysis. The potential risk of seizures from TMS is mitigated through careful screening, adhering to safety guidelines. The study's main benefit is enhancing dystonic behavior and deepening the understanding of brain changes caused by TMS in focal hand dystonia, paving the way for further advancements in clinical therapy for this condition.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06015672 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Duke University
- Last refreshed: 11 March 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06015672.
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