NCT06012669 is a NA clinical trial of High dose Human Lactoferrin in Immune Health, sponsored by Midwest Center for Metabolic and Cardiovascular Research.

Who is sponsoring NCT06012669?

NCT06012669 is sponsored by Midwest Center for Metabolic and Cardiovascular Research.

What drugs are being tested in NCT06012669?

Interventions in NCT06012669: High dose Human Lactoferrin, Low dose Human Lactoferrin, Active Control Bovine Lactoferrin.

What condition does NCT06012669 study?

NCT06012669 studies Immune Health.

Is NCT06012669 still recruiting?

NCT06012669 is currently completed. Last updated 11 June 2025.

Last reviewed 2025-06-11 · How we verify

NCT06012669

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Effects of Lactoferrin at Two Doses vs. Active Control on Markers of Immune Function

Completed NA Last updated 11 June 2025

What this trial tests

NA trial testing High dose Human Lactoferrin in Immune Health in 66 participants. Completed in 27 December 2023.

Timeline

6 September 2023

Primary endpoint
27 December 2023

27 December 2023

Quick facts

Lead sponsor	Midwest Center for Metabolic and Cardiovascular Research
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	quadruple
Primary purpose	other
Enrollment	66
Start date	6 September 2023
Primary completion	27 December 2023
Estimated completion	27 December 2023
Sites	2 locations across United States

Drugs / interventions tested

High dose Human Lactoferrin
Low dose Human Lactoferrin
Active Control Bovine Lactoferrin

Conditions studied

Immune Health — all drugs for Immune Health →

Sponsor

Midwest Center for Metabolic and Cardiovascular Research

Who can join

Adults 18 to 45, any sex, with Immune Health. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The purpose of this study is to evaluate the impact of 28-day supplementation with high-dose human recombinant lactoferrin, low-dose human recombinant lactoferrin, and an active control product formulated with bovine lactoferrin on indicators of immunity in healthy males and females.

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

A Randomized, Double-Blind, Controlled Trial to Assess the Effects of Lactoferrin at Two Doses vs. Active Control on Immunological and Safety Parameters in Healthy Adults.
Peterson RD, Guarneiri LL, Adams CG, Wilcox ML, et al · · 2025 · cited 6× · PMID 39465888 · DOI 10.1177/10915818241293723
A Randomized, Double-Blind, Controlled Trial to Assess the Effects of Lactoferrin at Two Doses vs. Active Control on Immunological and Safety Parameters in Healthy Adults
Peterson RD, Guarneiri LL, Adams CG, Wilcox ML, et al · · 2024 · cited 1× · DOI 10.1101/2024.07.17.24310517
Effects of Human Lactoferrin (Effera<sup>®</sup>) at Two Doses Versus Bovine Lactoferrin on the Adult Gut Microbiome and Fecal Short-Chain Fatty Acids: a Randomized, Double-Blind Trial.
Peterson RD, van der Made J, Donovan SM, Wang M, et al · · 2026 · PMID 42178844 · DOI 10.1080/19390211.2026.2673021

Verify or expand the search:

Other Midwest Center for Metabolic and Cardiovascular Research trials

Trials by the same sponsor.

NCT07293091 — Assessing the Appearance of Amino Acids in Circulation Following Consumption of Protein Beverages · NA · completed
NCT07012317 — A Trial to Assess Gastrointestinal Responses to Dietary Fibers in Adults Using Weight Loss Medications · NA · completed
NCT06923332 — A Trial to Assess the Effects of Diets With and Without Inulin on Energy Expenditure in Adults. · NA · completed
NCT06494449 — Effect of Acute Intake of Meals Containing Higher vs. Lower Energy From Protein on DIT · NA · completed
NCT06269094 — A Study to Understand How Continuous Glucose Monitors Impact Eating Behavior · NA · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT06012669 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Midwest Center for Metabolic and Cardiovascular Research
Last refreshed: 11 June 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06012669.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing