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NCT06011161: BRC

A Pilot of the Brief Relationship Checkup

Completed NA Results posted Last updated 1 October 2024
What this trial tests

NA trial testing Brief Relationship Checkup (BRC) in Relationship Distress in 40 participants. Completed in 20 July 2021.

Timeline
28 January 2020
Primary endpoint
20 July 2021
20 July 2021

Quick facts

Lead sponsorCanandaigua VA Medical Center
PhaseNA
StatusCompleted
Study typeINTERVENTIONAL
Allocationna
Designsingle group
Maskingnone
Primary purposetreatment
Enrollment40
Start date28 January 2020
Primary completion20 July 2021
Estimated completion20 July 2021
Sites1 location across United States

Drugs / interventions tested

Conditions studied

Sponsor

Canandaigua VA Medical Center

Who can join

18 and older, any sex, with Relationship Distress. Patients with the condition only — healthy volunteers not accepted.

Results — posted to ClinicalTrials.gov

Per-arm endpoint measurements with 95% confidence intervals where reported. Source: trial results section.

Relationship Functioning Primary · Pre-treatment

Relationship Functioning will be measured using the Couples Satisfaction Index (CSI). The self-report scale has a minimum of 0 and a maximum of 161 with higher scores representing more satisfying relationships and scores \< 104.5 classified as "distressed." The CSI is widely used in couple therapy research and is used routinely in VA care to evaluate Veterans' progress in evidence-based couple therapies.

GroupValue95% CI
Screened Veteran84.99± 6.60
Second Partner90.90± 6.60
Relationship Functioning Primary · After Completing the BRC Program (1-3months after pre-treatment)

Relationship Functioning will be measured using the Couples Satisfaction Index (CSI). The self-report scale has a minimum of 0 and a maximum of 161 with higher scores representing more satisfying relationships and scores \< 104.5 classified as "distressed." The CSI is widely used in couple therapy research and is used routinely in VA care to evaluate Veterans' progress in evidence-based couple therapies.

GroupValue95% CI
Screened Veteran117.66± 6.97
Second Partner106.81± 6.88
Emotional Intimacy/Mutual Responsiveness Secondary · Pre-treatment

Emotional Intimacy will be measured using the Perceived Responsiveness \& Insensitivity Scale (PRI). The PRI is an optimized measure of "Perceived Partner Responsiveness," a model of emotional intimacy that is widely used in the field to understand whether partners see one another as understanding/validating. The PRI has a minimum of 0 and a maximum of 80, with higher scores indicating greater sense of validation/understanding from one's partner.

GroupValue95% CI
Screened Veteran41.64± 4.49
Second Partner44.80± 4.49
Emotional Intimacy/Mutual Responsiveness Secondary · After Completing the BRC Program (1-3months after pre-treatment)

Emotional Intimacy will be measured using the Perceived Responsiveness \& Insensitivity Scale (PRI). The PRI is an optimized measure of "Perceived Partner Responsiveness," a model of emotional intimacy that is widely used in the field to understand whether partners see one another as understanding/validating. The PRI has a minimum of 0 and a maximum of 80, with higher scores indicating greater sense of validation/understanding (i.e., greater emotional intimacy).

GroupValue95% CI
Screened Veteran58.87± 4.65
Second Partner50.67± 4.61
Depressive Symptoms Secondary · Pre-treatment

Depression will be measured using the 9-item Patient Health Questionnaire (PHQ-9). This self-report scale has a minimum of 0 and a maximum of 27 with higher scores representing greater number and frequency of depression symptoms and scores of 10 or higher representing moderate depression.

GroupValue95% CI
Screened Veteran11.00± 0.98
Second Partner7.50± 0.98
Depressive Symptoms Secondary · After Completing the BRC Program (1-3months after pre-treatment)

Depression will be measured using the 9-item Patient Health Questionnaire (PHQ-9). This self-report scale has a minimum of 0 and a maximum of 27 with higher scores representing greater number and frequency of depression symptoms and scores of 10 or higher representing moderate depression.

GroupValue95% CI
Screened Veteran8.17± 1.08
Second Partner4.24± 1.06
Perceived Burdensomeness Secondary · Pre-treatment

Perceived burdensomeness will be measured with the burden-specific subscale of the Interpersonal Needs Questionnaire (INQ). This self-report scale has a minimum of 6 and a maximum of 42 with higher scores representing a stronger belief that one is a burden on others. Scores of 12 or higher predict a higher risk for developing suicidal ideation.

GroupValue95% CI
Screened Veteran11.14± 1.05
Second Partner7.84± 1.07
Perceived Burdensomeness Secondary · After Completing the BRC Program (1-3months after pre-treatment)

Perceived burdensomeness will be measured with the burden-specific subscale of the Interpersonal Needs Questionnaire (INQ). This self-report scale has a minimum of 6 and a maximum of 42 with higher scores representing a stronger belief that one is a burden on others. Scores of 12 or higher predict a higher risk for developing suicidal ideation.

GroupValue95% CI
Screened Veteran9.76± 1.09
Second Partner7.06± 1.09
Thwarted Belongingness Secondary · Pre-treatment

Thwarted belongingness will be measured with the belonging-specific subscale of the Interpersonal Needs Questionnaire (INQ). This self-report scale has a minimum of 9 and a maximum of 63 with higher scores representing a stronger feeling of loneliness and isolation. Scores of 36 or higher predict a higher risk for developing suicidal ideation.

GroupValue95% CI
Screened Veteran31.26± 2.43
Second Partner28.32± 2.47
Thwarted Belongingness Secondary · After Completing the BRC Program (1-3months after pre-treatment)

Thwarted belongingness will be measured with the belonging-specific subscale of the Interpersonal Needs Questionnaire (INQ). This self-report scale has a minimum of 9 and a maximum of 63 with higher scores representing a stronger feeling of loneliness and isolation. Scores of 36 or higher predict a higher risk for developing suicidal ideation.

GroupValue95% CI
Screened Veteran23.75± 2.55
Second Partner23.50± 2.55
Suicide Ideation Severity Secondary · Pre-treatment

Suicide ideation over the study will be monitored using the "Last Month" version of the Columbia Suicide Severity Rating Scale (CSSRS). This semi-structured interview has interviewers rate suicide ideation on a scale of 0 to 5, with scores of 3-5 placing individuals at high risk for attempt. VA hospitals use the C-SSRS across all clinics.

GroupValue95% CI
Screened Veteran18
Second Partner20
Screened Veteran1
Second Partner0
Screened Veteran1
Second Partner0
Suicide Ideation Severity Secondary · After Completing the BRC Program (1-3months after pre-treatment)

Suicide ideation over the study will be monitored using the "Last Month" version of the Columbia Suicide Severity Rating Scale (CSSRS). This semi-structured interview has interviewers rate suicide ideation on a scale of 0 to 5, with scores of 3-5 placing individuals at high risk for attempt. VA hospitals use the C-SSRS across all clinics.

GroupValue95% CI
Screened Veteran14
Second Partner17
Screened Veteran2
Second Partner0
Screened Veteran0
Second Partner0

Adverse events — posted to ClinicalTrials.gov

Time frame: Study duration from first to last assessment (1-3 months).. Reporting threshold: 0%. Adverse-event reports describe events observed during the trial — not all are caused by the drug.

Screened Veteran
Serious: 0/20 (0%)
Deaths: 0/20
Second Partner
Serious: 0/20 (0%)
Deaths: 0/20
Other adverse events (3 terms — click to expand)

ReactionSystemScreened VeteranSecond Partner
Intimate Partner Violence EventSocial circumstances
Non-Suicidal Self-InjuryPsychiatric disorders
Suicidal BehaviorPsychiatric disorders

Data from ClinicalTrials.gov NCT06011161 adverse events section.

Sponsor's own description

The goal of this pilot trial is to study the Brief Relationship Checkup (BRC) program for Veterans with a combination of mental health and relationship concerns. BRC has been studied in Air Force primary care, but has never been tested in the Department of Veterans Affairs. To prepare for a larger study of BRC, the investigators asked the following questions: 1. Can the research team deliver BRC to Veterans with mental health concerns? ("Feasibility") 2. What is the best way to measure BRC's impact? ("Pilot Outcomes") 3. Does BRC fit the needs of Veterans, and if not, what changes would fit participants' needs? ("Refinement") Participants completed an initial interview, attended the BRC program, and completed a follow-up interview.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

Other trials of Brief Relationship Checkup (BRC)

Trials testing the same drug.

Other recruiting trials for Relationship Distress

Currently open trials in the same condition.

Other Canandaigua VA Medical Center trials

Trials by the same sponsor.

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Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06011161.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing