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NCT06002087
Unified Protocol for Transdiagnostic Treatment for Depression and Anxiety in Adults
NA trial testing Unified Protocol for Transdiagnostic Treatment of Emotional Disorders in Depression in 51 participants. Completed in 15 March 2024.
31 December 2023
Quick facts
| Lead sponsor | National University of Science and Technology, Pakistan |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 51 |
| Start date | 1 August 2023 |
| Primary completion | 31 December 2023 |
| Estimated completion | 15 March 2024 |
| Sites | 1 location across Pakistan |
Drugs / interventions tested
- Unified Protocol for Transdiagnostic Treatment of Emotional Disorders
Conditions studied
- Depression — all drugs for Depression →
- Anxiety — all drugs for Anxiety →
Sponsor
National University of Science and Technology, Pakistan
Who can join
Adults 18 to 60, any sex, with Depression or Anxiety. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
To conduct a pilot randomized controlled trial (RCT) of a culturally adapted Unified Protocol (UP) for transdiagnostic psychological treatment in adults (age 18 and above) with anxiety and/or depression to assess the feasibility and acceptability of UP treatment. The main questions it aims to answer are: 1. To assess the estimates of likely recruitment rates including how many approached, volunteered, screened, retained, and complete the treatment and what is the dropout rate? 2. To what degree do participants adhere and engage with the treatment procedures? 3. To what extent do the participants feel satisfied with the treatment? 4. To what degree do participants complete self-report and clinician-administered measures of anxiety, depression, functional impairment, and emotion regulation? 5. What is the treatment outcome with regard to emotion regulation, symptoms of anxiety, depression, functional impairment, and emotion regulation? The participants will be randomized to either the treatment group or the control group. The treatment group will receive 14 sessions of one-on-one individual treatment with the Unified Protocol. The control group will receive no treatment.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Feasibility and Acceptability of the Unified Protocol for Anxiety and Depression in Pakistan: A Pilot Randomized Controlled Trial
Nisa¹ A, Siddiqui¹ S, Ametaj² AA. · · 2026 · DOI 10.21203/rs.3.rs-9241321/v1 -
Clinical Trials and Therapeutic Approaches for Healthcare Challenges in Pakistan
Ahmed A, Williams N. · · 2023
Verify or expand the search:
- PubMed search for NCT06002087
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Unified Protocol for Transdiagnostic Treatment of Emotional Disorders
Trials testing the same drug.
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- NCT05357586 — The Pitt Center for Emergency Responder Wellness · NA · completed
- NCT04612374 — Exploring the Acceptability and Efficacy of a Transdiagnostic Treatment for Misophonia · NA · completed
- NCT04198597 — Exploring Two Treatments for Misophonia · NA · completed
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Other National University of Science and Technology, Pakistan trials
Trials by the same sponsor.
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- NCT06582303 — Analysis of the Effectiveness of Visual Training in Stroke Rehabilitation · NA · completed
- NCT05216445 — Mindfulness for Stress and Well-being in University Students · NA · completed
- NCT04222049 — Application of Vibration Wave Therapy to the Children Suffering From Cerebral Palsy and Tongue Spastic Dysarthria · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06002087 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by National University of Science and Technology, Pakistan
- Last refreshed: 29 June 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06002087.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing