NCT05996068: ALTR

Arterial Line in Trauma Resuscitation

Active, enrolled NA Last updated 13 November 2024

What this trial tests

NA trial testing arterial line in Major Trauma in 216 participants. Participants enrolled and being followed up; not accepting new ones.

Timeline

1 January 2023

Primary endpoint
31 December 2024

30 June 2025

Quick facts

Lead sponsor	National Taiwan University Hospital
Phase	NA
Status	Active, enrolled
Study type	INTERVENTIONAL
Allocation	non randomized
Design	single group
Masking	none
Primary purpose	diagnostic
Enrollment	216
Start date	1 January 2023
Primary completion	31 December 2024
Estimated completion	30 June 2025
Sites	1 location across Taiwan

Drugs / interventions tested

• arterial line

Conditions studied

• Major Trauma — all drugs for Major Trauma →

Sponsor

National Taiwan University Hospital

Who can join

18 and older, any sex, with Major Trauma. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Accident-related deaths is the 7th leading cause of death in Taiwan, and most of them is due to trauma from falls and traffic accident. Among trauma patients, the common cause of death is from hemorrhagic shock. Thus, real-time and accurate blood pressure monitoring is important for trauma patients. Incorrect blood pressure monitoring can lead to adverse events like traumatic cardiac arrest and shock and can also delay the time for intervention (fluid resuscitation, blood transfusion and operation). The current practice of blood pressure monitoring in trauma patient is by non-invasive blood pressure monitoring, which may be incorrect and not timely. Patient's body type and peripheral perfusion can both influence the result of non-invasive blood pressure monitoring.

With continuous and correct blood pressure monitoring, the resuscitation team can give adequate and timely treatment. In some trauma centers, arterial line insertion in trauma patients is a daily practice, while the evidence is inadequate and the potential benefit in unknown.

The main purpose of this study is to investigate the application of arterial line insertion in trauma patients. The study design is a prospective before-after study to exam whether arterial line insertion in trauma patients can reduce adverse event rate like hypovolemic shock and improve patient's outcomes.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.