Last reviewed · How we verify
Effect of Sodium Glucose Co-transporter 2 Inhibitors on Left Atrium Remodeling in Non-valvular Paroxysmal Atrial Fibrillation Patients
Investigators are going to assess direct effect of SGLT2 inhibitors on left atrial remodeling in participants with nonvalvular paroxysmal atrial fibrillation regardless of diabetes status.
Details
| Lead sponsor | Aswan University |
|---|---|
| Phase | NA |
| Status | UNKNOWN |
| Enrolment | 60 |
| Start date | 2023-08 |
| Completion | 2024-12 |
Conditions
- Atrial Fibrillation
Interventions
- Sodium Glucose Co-transporter 2 (SGLT2) Inhibitor
- Rhythm control and anticoagulation
Primary outcomes
- Left atrial remodeling — Before first administration of treatment and will be repeated 6 months after while still on treatment
by measuring Indexed LA volume (LAVI) in ml/m2 - Changes in left atrial strain — Before first administration of treatment and will be repeated 6 months after while still on treatment
by measuring left atrial strain % - Changes in left atrial systolic force — Before first administration of treatment and will be repeated 6 months after while still on treatment
by measuring left atrial systolic force in ml/m3