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NCT05993533: QuantiXa

Comparison of the 'CTR' Ratio With Standard Haemostasis Parameters in the Follow-up of Patients Undergoing Heparin Therapy

Status unknown Last updated 15 August 2023
What this trial tests

trial in Venous Thromboembolic Disease in 100 participants. Status unknown.

Timeline
22 June 2023
Primary endpoint
22 December 2023
31 December 2023

Quick facts

Lead sponsorDirection Centrale du Service de Santé des Armées
StatusStatus unknown
Study typeOBSERVATIONAL
Enrollment100
Start date22 June 2023
Primary completion22 December 2023
Estimated completion31 December 2023
Sites1 location across France

Conditions studied

Sponsor

Direction Centrale du Service de Santé des Armées — full company profile →

Who can join

Adults 18 to 65, any sex, with Venous Thromboembolic Disease. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The Quantra(r) hemostasis analyzer (Stago) is a recent addition to the family of global hemostasis tests. It uses ultrasound-based technology to characterize the viscoelastic properties of a whole blood sample during coagulation. The Qplus(r) cartridge consists of independent channels, each containing different reagents that provide parallel measurements of 6 parameters. This global test takes into account cellular elements such as platelets and red blood cells in clot formation, and also explores fibrinolysis. In addition, this test is of particular interest in delocalized biology, i.e. at the patient's bedside, and avoids the time-consuming laboratory centrifugation stage required for routine analyzers. In practice, this test has been developed to monitor haemostasis in patients who may present with a range of coagulopathies of various etiologies, but also in the management of haemorrhagic patients, in order to adapt the administration of blood products in particular. The Quantra (r) analyzer could therefore be of interest since it could be deployed in overseas operations to manage war casualties. Recent studies (EACTAIC-ICCVA congress, October 2021) have shown that there is a good correlation between anti-Xa activity and the CTR (coagulation time ratio) parameter of the Quantra cartridge Qplus (TM), suggesting that this automated system could be used to manage anticoagulant therapy.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

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Other recruiting trials for Venous Thromboembolic Disease

Currently open trials in the same condition.

Other Direction Centrale du Service de Santé des Armées trials

Trials by the same sponsor.

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Data sources for this page

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