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Relation Between Psychoactive Drugs Overdosage and Severity of Falls in Elderly People (MEDIFALL)
There are many epidemiological data on the relationship between the number or nature of psychoactive medications used and the risk of falling in elderly, but very little on the relationship between the amount of psychoactive medication actually present in the blood and the severity of the fall. However, the inevitable drug-drug interactions related to polypharmacy and the pharmacokinetic modifications related to old age may lead plasma overdose situations which can potentiate the risk of falls but also aggravate these consequences. The investigators therefore propose a study with the objective of verifying whether the proportion of falls with serious traumatic consequences is more frequent in patients over 75 years old, presenting plasma overdoses of psychoactive drugs (plasma concentrations higher than the usual therapeutic concentrations) in regard to those between therapeutic ranges. The aim of this work is to verify if the falls present more severe characters when the psychoactive drug concentrations are beyond the usual therapeutic ranges.
Details
| Lead sponsor | University Hospital, Caen |
|---|---|
| Phase | NA |
| Status | RECRUITING |
| Enrolment | 400 |
| Start date | Wed May 22 2024 00:00:00 GMT+0000 (Coordinated Universal Time) |
| Completion | Tue May 30 2028 00:00:00 GMT+0000 (Coordinated Universal Time) |
Conditions
- Fall
Interventions
- Blood sampling for psychoactive drugs dosage
Countries
France