NCT05985538

Impact of E-Cigarette Prevention Messages on Adolescents

Completed NA Results posted Last updated 22 August 2025

What this trial tests

NA trial testing Vaping prevention text messages in Vaping Behavior in 480 participants. Completed in 12 August 2024.

Timeline

5 February 2024

Primary endpoint
30 June 2024

12 August 2024

Quick facts

Lead sponsor	UNC Lineberger Comprehensive Cancer Center
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	prevention
Enrollment	480
Start date	5 February 2024
Primary completion	30 June 2024
Estimated completion	12 August 2024
Sites	1 location across United States

Drugs / interventions tested

• Vaping prevention text messages
• Wellness behaviors text messages

Conditions studied

• Vaping Behavior — all drugs for Vaping Behavior →

Sponsor

UNC Lineberger Comprehensive Cancer Center — full company profile →

Who can join

Adults 13 to 20, any sex, with Vaping Behavior. Patients with the condition only — healthy volunteers not accepted.

Results — posted to ClinicalTrials.gov

Per-arm endpoint measurements with 95% confidence intervals where reported. Source: trial results section.

Mean Susceptibility to Vaping Score Primary · Visit 3 (4 weeks)

The mean susceptibility to vaping score will be assessed using the questionnaire. Response options are on a 1 to 4 scale. Overall scale scores are determined by summing scores of the 3 items and dividing them by 3 (range 1-4), with higher scores representing a greater susceptibility to vaping (a worse outcome).

Group	Value	95% CI
Vaping Prevention Text Messages	1.91	± 1.01
Wellness Behavior Text Messages	1.82	± 0.88

Mean Vaping Instrumental Attitudes Score Secondary · Visit 3 (4 weeks)

The mean vaping instrumental attitudes score will be assessed using the questionnaire. Response options are on a 1 to 5 scale. Overall scale scores are determined by summing scores of the 3 items and dividing them by 3 (range 1-5), with higher scores representing a belief that vaping is more beneficial, safe and healthy.

Group	Value	95% CI
Vaping Prevention Text Messages	1.56	± 0.82
Wellness Behavior Text Messages	1.67	± 0.79

Mean Vaping Affective Attitudes Score Secondary · Visit 3 (4 weeks)

.The mean vaping affective attitudes score will be assessed using the questionnaire. Response options are on a 1 to 5 scale. Overall scale scores are determined by summing scores of the 3 items and dividing them by 3 (range 1-5), with higher scores representing a belief that vaping is more enjoyable, pleasant, and fun.

Group	Value	95% CI
Vaping Prevention Text Messages	2.31	± 1.13
Wellness Behavior Text Messages	2.28	± 1.16

Mean Vaping Addiction Risk Beliefs Score Secondary · Visit 3 (4 weeks)

The mean vaping addiction risk beliefs score will be assessed using the questionnaire. Response options are on a 1 to 5 scale. Overall scale scores are determined by summing scores of the 3 items and dividing them by 3 (range 1-5), with higher scores representing more tendency to addiction.

Group	Value	95% CI
Vaping Prevention Text Messages	3.70	± 1.30
Wellness Behavior Text Messages	3.28	± 1.29

Mean Vaping Monetary Cost Beliefs Score Secondary · Visit 3 (4 weeks)

The mean vaping monetary cost beliefs score will be assessed using the questionnaire. Response options are on a 1 to 5 scale. Overall scale scores are determined by summing scores of the 3 items and dividing them by 3 (range 1-5), with higher scores represents participants' believes that vaping is a costly activity.

Group	Value	95% CI
Vaping Prevention Text Messages	3.63	± 1.50
Wellness Behavior Text Messages	3.46	± 1.51

Mean Vaping Chemical Risk Beliefs Score Secondary · Visit 3 (4 weeks)

The mean vaping chemical risk beliefs score will be assessed using the questionnaire. Response options are on a 1 to 5 scale. Overall scale scores are determined by summing scores of the 3 items and dividing them by 3 (range 1-5), with higher scores representing participant's believes that e-cigarette vapor contains chemicals that pose health risks.

Group	Value	95% CI
Vaping Prevention Text Messages	4.16	± 1.09
Wellness Behavior Text Messages	4.04	± 1.19

Mean Vaping Cosmetic Risk Beliefs Score Secondary · Visit 3 (4 weeks)

The mean vaping cosmetic risk beliefs score will be assessed using the questionnaire. Response options are on a 1 to 5 scale. Overall scale scores are determined by summing scores of the 3 items and dividing them by 3 (range 1-5), with higher scores representing participant belief that use will harm their cosmetic appearance.

Group	Value	95% CI
Vaping Prevention Text Messages	3.97	± 1.09
Wellness Behavior Text Messages	3.63	± 1.25

Mean Vaping Health Symptoms Beliefs Score Secondary · Visit 3 (4 weeks)

The mean vaping physical symptoms of use beliefs score will be assessed using the questionnaire. Response options are on a 1 to 5 scale. Overall scale scores are determined by summing scores of the 3 items and dividing them by 3 (range 1-5), with higher scores represent participant believes that e-cigarette use will cause certain physical symptoms.

Group	Value	95% CI
Vaping Prevention Text Messages	3.92	± 1.09
Wellness Behavior Text Messages	3.77	± 1.15

Mean Vaping Mental Health Symptoms of Use Beliefs Score Secondary · Visit 3 (4 weeks)

The mean vaping mental health symptoms of use beliefs score will be assessed using the questionnaire. Response options are on a 1 to 5 scale. Overall scale scores are determined by summing scores of the 3 items and dividing them by 3 (range 1-5), with higher scores represent participant believes that e-cigarette use will cause or worsen mental health symptoms.

Group	Value	95% CI
Vaping Prevention Text Messages	3.82	± 1.13
Wellness Behavior Text Messages	3.39	± 1.23

Mean Vaping Health Organ Risk Beliefs Score Secondary · Visit 3 (4 weeks)

The mean vaping health organ risk beliefs score will be assessed using the questionnaire. Response options are on a 1 to 5 scale. Overall scale scores are determined by summing scores of the 3 items and dividing them by 3 (range 1-5), with higher scores representing participant believes that e-cigarette use will harm the health of certain organs.

Group	Value	95% CI
Vaping Prevention Text Messages	4.19	± 1.04
Wellness Behavior Text Messages	4.02	± 1.13

Mean Susceptibility to Smoking Cigarettes Score Secondary · Visit 3 (4 weeks)

The mean susceptibility to smoking cigarettes score will be assessed using the questionnaire. Response options are on a 1 to 5 scale. Overall scale scores are determined by summing scores of the 3 items and dividing them by 3 (range 1-5), with higher scores represent participant more open to smoking.

Group	Value	95% CI
Vaping Prevention Text Messages	1.46	± .78
Wellness Behavior Text Messages	1.42	± .70

Mean Smoking Instrumental Attitude Score Secondary · Visit 3 (4 weeks)

The 1-item mean smoking instrumental attitude measure assesses a participant's attitude toward smoking. Response options are on a 1 to 5 scale, with higher scores representing a more harmful perception of smoking.

Group	Value	95% CI
Vaping Prevention Text Messages	1.41	± .85
Wellness Behavior Text Messages	1.39	± .87

Sponsor's own description

The purpose of this trial is to determine whether a vaping prevention text message program reduces susceptibility to vaping among adolescents and young adults. This study addresses this issue by exposing participants to a vaping prevention text message program over a 28-day period in a randomized controlled trial with a matched attention control condition. A follow-up assessment is also made 4 weeks after the text messaging ends.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.