NCT05984524 (NUGammaMBI) is a NA clinical trial of Gamma-Music Based Intervention in Alzheimer Disease, sponsored by Northeastern University.

Who is sponsoring NCT05984524?

NCT05984524 is sponsored by Northeastern University.

What drugs are being tested in NCT05984524?

Interventions in NCT05984524: Gamma-Music Based Intervention.

What condition does NCT05984524 study?

NCT05984524 studies Alzheimer Disease.

Is NCT05984524 still recruiting?

NCT05984524 is currently recruiting now. Last updated 6 October 2023.

Last reviewed 2023-10-06 · How we verify

NCT05984524: NUGammaMBI

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Gamma-Music Based Intervention for Mild Alzheimer's Disease

Recruiting now NA Last updated 6 October 2023

What this trial tests

NA trial testing Gamma-Music Based Intervention in Alzheimer Disease in 60 participants. Currently enrolling.

Timeline

1 July 2022

Primary endpoint
30 June 2027

30 June 2027

Quick facts

Lead sponsor	Northeastern University
Phase	NA
Status	Recruiting now
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	other
Enrollment	60
Start date	1 July 2022
Primary completion	30 June 2027
Estimated completion	30 June 2027
Sites	1 location across United States

Drugs / interventions tested

Gamma-Music Based Intervention

Conditions studied

Alzheimer Disease — all drugs for Alzheimer Disease →

Sponsor

Northeastern University

Who can join

Adults 50 to 95, any sex, with Alzheimer Disease. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The study will test and refine a novel brain-stimulation tool using gamma-frequency lights coupled with self-selected music for a gamma-music-based intervention for participants with mild Alzheimer's Disease. Results will yield a gamma-stimulation protocol that reliably influences brain activity (Aim 1), is adaptive, motivating and rewarding to use (Aim 2), and will generate predictions as to who might benefit the most from gamma-MBI (Aim 3). By bridging the gap between neurostimulation and behavioral intervention by combining music therapy with gamma- band neurostimulation, the present project aims to find a sustainable intervention that delays the progression of AD.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Entraining the Brain with Music and Synchronized Light to Improve Memory and Preserve Cognitive Function
· 2025
Diary Analysis of an RCT: Natural Language Analyses of Gamma-Music-Based Intervention.
Kubit BM, Parrish C, Zhao Z, Loui P. · · 2025 · PMID 40291816 · DOI 10.47513/mmd.v17i1.1066

Verify or expand the search:

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Other Northeastern University trials

Trials by the same sponsor.

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NCT07139795 — The Mind-Body Project · NA · active not recruiting
NCT06645652 — Visual Arts Interventions With Older Adults · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05984524 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Northeastern University
Last refreshed: 6 October 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05984524.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing