NCT05983224 is a NA clinical trial of Quercetin in Endometriosis, sponsored by National Nutrition and Food Technology Institute.

Who is sponsoring NCT05983224?

NCT05983224 is sponsored by National Nutrition and Food Technology Institute.

What drugs are being tested in NCT05983224?

Interventions in NCT05983224: Quercetin, Placebo.

What condition does NCT05983224 study?

NCT05983224 studies Endometriosis.

Is NCT05983224 still recruiting?

NCT05983224 is currently status unknown. Last updated 16 August 2023.

Last reviewed 2023-08-16 · How we verify

NCT05983224

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Effect of Quercetin Supplementation on Endometriosis Outcomes

Status unknown NA Last updated 16 August 2023

What this trial tests

NA trial testing Quercetin in Endometriosis in 50 participants. Status unknown.

Timeline

15 August 2023

Primary endpoint
1 January 2024

1 March 2024

Quick facts

Lead sponsor	National Nutrition and Food Technology Institute
Phase	NA
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	quadruple
Primary purpose	supportive care
Enrollment	50
Start date	15 August 2023
Primary completion	1 January 2024
Estimated completion	1 March 2024
Sites	1 location across Iran

Drugs / interventions tested

Quercetin (QUERCETIN) — full drug profile →
Placebo

Conditions studied

Endometriosis — all drugs for Endometriosis →

Sponsor

National Nutrition and Food Technology Institute

Who can join

Adults 18 to 40, female only, with Endometriosis. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Quercetin is a polyphenol compound that possesses anti-inflammatory properties and can be found in various food sources like apples, berries, cabbage, and onions. In Park et al.'s study, it was discovered that quercetin led to a significant decrease in the proliferation of endometriosis cells. Furthermore, quercetin also triggered apoptosis in endometriosis cells in vitro and reduced the size of endometriosis lesions in vivo. Nevertheless, as of now, there have been no studies conducted in Iran or worldwide that explore the effects of quercetin supplementation on individuals with endometriosis. Hence, the aim of this study is to investigate the impact of quercetin supplementation on factors such as glycemic status, lipid profile, oxidative stress, inflammation, growth factors, adiponectin, sex hormones, and anthropometric indicators in women suffering from endometriosis.

Publications & conference data

5 peer-reviewed publications reference this trial (live from Europe PMC):

Registration and characteristics of clinical trials on traditional Chinese medicine and natural medicines for endometriosis: a comprehensive analysis.
Zhao Y, Wang Y, Xue Z, Weng Y, et al · · 2024 · cited 3× · PMID 39564497 · DOI 10.3389/fmed.2024.1432815
Effects of quercetin and its derivatives in in vivo models of neuroinflammation: A systematic review and meta-analysis.
Dos Santos MG, Arbo BD, Hort MA. · · 2026 · cited 2× · PMID 40145967 · DOI 10.4103/nrr.nrr-d-24-01175
Endometriosis: new insights and opportunities for relief of symptoms.
Saunders PTK, Horne AW. · · 2025 · cited 1× · PMID 40704733 · DOI 10.1093/biolre/ioaf164
Natural products modulate programmed cell death signaling mechanism for treating endometriosis: a review.
Zhao Z, Liu F, Yu Y, Shen Y, et al · · 2026 · PMID 41693781 · DOI 10.3389/fphar.2026.1742212
Research progress on natural plant metabolites targeting apoptosis for endometriosis prevention and treatment: a systematic review.
Yu Y, Zhu Y, Gao M, Wang Y, et al · · 2025 · PMID 40703363 · DOI 10.3389/fphar.2025.1624569

Verify or expand the search:

Other trials of Quercetin

Trials testing the same drug.

NCT07144293 — Improving Physical Ability and Cellular Senescence Elimination in HIV · Phase 2 · active not recruiting
NCT07182526 — Effects of Adding Quercetin or Alpha Lipoic Acid to Usual Care on Symptoms and Blood Markers in Iraqi Women With Polycys · Phase 2 · recruiting
NCT07025226 — Sequential Treatments or Combinations Including Dasatinib, Quercetin, Fisetin and/or Temozolomide for the Treatment of P · EARLY_PHASE1 · recruiting
NCT06940297 — Dasatinib and Quercetin With CAR-T Therapy for the Treatment of Patients With Relapsed or Refractory Multiple Myeloma · Phase 2 · recruiting
NCT07380178 — The Effect of Apple Fruit Extract (Malus Sylvestris Mill) as an Antioxidant and Anti-Inflammatory on Allergic Rhinitis · NA · completed

Other recruiting trials for Endometriosis

Currently open trials in the same condition.

NCT06559852 — The Impact of Yoga on Endometriosis-Related Pain · NA · recruiting
NCT07393295 — Efficacy and Tolerability of TENS in Endometriosis-related Pain · NA · recruiting
NCT07134023 — Educational Program for the Multidisciplinary Support of Patients With Endometriosis · NA · recruiting
NCT07240883 — ENDO1000 - A UK-wide Endometriosis Research Project · recruiting
NCT06974773 — Remote Electrical Stimulation as a Long-term Intervention for Endometriosis Flare Ups · NA · recruiting

Other National Nutrition and Food Technology Institute trials

Trials by the same sponsor.

NCT06900946 — Evaluation of the Effects of Gluten Free Diet on Clinical Symptoms and Glycemic Index in Type 2 Diabetic Patients With N · NA · enrolling by invitation
NCT06351696 — The Effects of Bromelain Supplement in Patients With Ulcerative Colitis · NA · recruiting
NCT06353633 — The Effect of Exclusion Diet for Crohn's Disease Plus Enteral Nutrition on Children and Adolescents With Crohn's Disease · NA · not yet recruiting
NCT06160830 — The Effects of Synbiotic on Cardiovascular and Bone Metabolism Markers in Transplanted Kidney Patients · NA · unknown
NCT06096558 — The Effects of Melatonin on Cardiovascular and Bone Metabolism Markers in Peritoneal Dialysis Patients · NA · unknown

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05983224 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by National Nutrition and Food Technology Institute
Last refreshed: 16 August 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05983224.

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