Last reviewed · How we verify
NCT05980494
Lung Ultrasound Score and Inferior Vena Cava Diameter Compared to Pulse Pressure Variation
NA trial testing normal Saline in Sepsis in 150 participants. Completed in 20 June 2024.
20 May 2024
Quick facts
| Lead sponsor | Fayoum University Hospital |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | diagnostic |
| Enrollment | 150 |
| Start date | 13 September 2022 |
| Primary completion | 20 May 2024 |
| Estimated completion | 20 June 2024 |
| Sites | 1 location across Egypt |
Drugs / interventions tested
- normal Saline
- lung ultrasound
- inferior vena cava measurements
- passive leg raising test (PLRT)
- pulse pressure variation
Conditions studied
- Sepsis — all drugs for Sepsis →
- Critical Illness — all drugs for Critical Illness →
Sponsor
Fayoum University Hospital
Who can join
18 and older, any sex, with Sepsis or Critical Illness. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Evaluation and management of intravascular volume are a central challenge for the critical ill patients. Hypotensive patients are commonly resuscitated with intravenous crystalloid fluid as a recommendation for treatment of many shock states. There has been a growing interest in the implementation of lung ultrasound in critical care management in the last decade as it is easy, bedside, non-expensive, non invasive and radiation free. The object of the current study is to assess the ability of lung and inferior vena cava sonography versus pulse pressure variation to predict fluid responsiveness in patients with circulatory failure on mechanical ventilation.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT05980494
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of normal Saline
Trials testing the same drug.
- NCT06729047 — Prophylactic Intravenous Injection of Neostigmine Plus Atropine Versus Ketorolac on Post-dural Puncture Headache in Pati · Phase 1, PHASE2 · not yet recruiting
- NCT06575179 — Dexmedetomidine Reduces Sevoflurane MAC-BAR During Pneumoperitoneum · Phase 4 · recruiting
- NCT06543563 — Esketamine in Microelectrode Recording-guided Subthalamic Deep-Brain Stimulation for Parkinson's Disease · NA · recruiting
- NCT06417125 — Intranasal Dexmedetomidine Versus Oral Midazolam Premedication for Postoperative Negative Behavior Changes in Children · Phase 4 · completed
- NCT06284668 — Esketamine vs Remimazolam for Postoperative Sleep Disturbance and Anxiety · NA · completed
Other recruiting trials for Sepsis
Currently open trials in the same condition.
- NCT07507877 — Infraclavicular Axillary Vein Collapsibility Index as a Predictor of Fluid Responsiveness · recruiting
- NCT07154615 — Assessing Immune Dysfunction in Sepsis · recruiting
- NCT07419802 — OxiCLEAR (Oxiris Cytokines and Endotoxin Adsorption Rate) Study · recruiting
- NCT07351344 — African Survey on Sepsis Knowledge (ASK) · recruiting
- NCT07448805 — Accuracy and Safety of the Syai Tag System for Continuous Glucose Monitoring in Intensive Internal Care Unit · NA · recruiting
Other Fayoum University Hospital trials
Trials by the same sponsor.
- NCT07507799 — Low Versus Standard Volume EXORA Block in Laparoscopic Cholecystectomy · NA · not yet recruiting
- NCT07435870 — Analgesia Nociception Index Monitoring in Trigeminal Cardiac Reflex During Nasal Septoplasty · not yet recruiting
- NCT07442721 — Sacral ESPB vs. PENG Block for Hip Hemiarthroplasty Analgesia · NA · recruiting
- NCT07187310 — EXORA vs ESP Blocks in Laparoscopic Cholecystectomy · NA · recruiting
- NCT07205757 — Adding Lidocaine to Custodiol Mixture · Phase 4 · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05980494 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Fayoum University Hospital
- Last refreshed: 12 March 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05980494.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing