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NCT05975593: METEOR-CRATR
MicroEnvironment Tumor Effects of Radiotherapy - Comprehensive Radiobiology Assessment TRial
NA trial testing Tumor collection via biopsy in Locally Advanced Cervical Carcinoma in 60 participants. Currently enrolling.
31 December 2032
Quick facts
| Lead sponsor | Washington University School of Medicine |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | non randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | diagnostic |
| Enrollment | 60 |
| Start date | 11 January 2024 |
| Primary completion | 31 December 2032 |
| Estimated completion | 31 December 2032 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Tumor collection via biopsy
- Blood collection — full drug profile →
- Diffusion basis spectrum imaging (DBSI) magnetic resonance imaging (MRI)
Conditions studied
- Locally Advanced Cervical Carcinoma — all drugs for Locally Advanced Cervical Carcinoma →
- Locally Advanced Cervical Cancer — all drugs for Locally Advanced Cervical Cancer →
- Locally Advanced Pancreas Cancer — all drugs for Locally Advanced Pancreas Cancer →
- Locally Advanced Pancreatic Carcinoma — all drugs for Locally Advanced Pancreatic Carcinoma →
Sponsor
Washington University School of Medicine
Who can join
18 and older, any sex, with Locally Advanced Cervical Carcinoma or Locally Advanced Cervical Cancer. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study is a dynamically adjustable prospective longitudinal study designed to capture biospecimen (biopsy, blood, surgical) and multimodal treatment-related data (imaging, dosimetry, clinical) before, during, and after treatment with definitive-intent chemoradiotherapy for patients with locally advanced cervical and pancreatic cancer.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Radiation Oncology-Biology Integration Network (ROBIN): Bridging the gap between biological research and clinical practice.
Gregucci F, Lee-Poturalski C, Dirrim M, Stewart J, et al · · 2026 · PMID 41941260 · DOI 10.1158/1078-0432.ccr-25-1216
Verify or expand the search:
- PubMed search for NCT05975593
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Locally Advanced Cervical Carcinoma
Currently open trials in the same condition.
- NCT06529809 — Accelerated Brachytherapy Forward Chemo Radiation Therapy (ABC-RT) for Locally-advanced Cervical Cancer · Phase 1, PHASE2 · recruiting
- NCT06398938 — Evaluation of Ultraaccelerated High Dose Rate Intrauterine Interventional Radiotherapy · recruiting
- NCT05722288 — Time-Restricted Eating Versus Nutritional Counseling for the Reduction of Radiation or Chemoradiation Tx Side Effects in · Phase 2 · recruiting
- NCT05462379 — Autologous Heterotopic Fresh Ovarian Graft in Woman With LACC Eligible for Pelvic Radiotherapy Treatment. · Phase 1, PHASE2 · active not recruiting
- NCT05406856 — PROTECT: On-line Adaptive Proton Therapy for Cervical Cancer · NA · recruiting
Other Washington University School of Medicine trials
Trials by the same sponsor.
- NCT05521997 — Glutaminase Inhibition and Chemoradiation in Advanced Cervical Cancer · Phase 2 · not yet recruiting
- NCT07101666 — Total Neoadjuvant Therapy With Short Course Radiation Therapy in Gastric Cancer · Phase 2 · not yet recruiting
- NCT07200089 — Recombinant Human IL-7 (NT-I7) in Relapsed/Refractory Multiple Myeloma Following BCMA CAR-T Therapy (Cilta-cel) · Phase 1 · not yet recruiting
- NCT07313592 — Whole Genome Sequencing (ChromoSeq®) for Acute Lymphoblastic Leukemia (ALL) Patients · not yet recruiting
- NCT07419464 — 5-Fluorouracil Response and Optimization STudy (The FROST Trial) · Phase 2 · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05975593 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Washington University School of Medicine
- Last refreshed: 12 November 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05975593.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing