NCT05974930 (ULTRA-STEMI) is a clinical trial of IVUS imaging for primary PCI guidance in STEMI, sponsored by Aristotle University Of Thessaloniki.

Who is sponsoring NCT05974930?

NCT05974930 is sponsored by Aristotle University Of Thessaloniki.

What drugs are being tested in NCT05974930?

Interventions in NCT05974930: IVUS imaging for primary PCI guidance.

What condition does NCT05974930 study?

NCT05974930 studies STEMI, Intravascular Imaging, IVUS.

Is NCT05974930 still recruiting?

NCT05974930 is currently status unknown. Last updated 3 August 2023.

Last reviewed 2023-08-03 · How we verify

NCT05974930: ULTRA-STEMI

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Intravascular ULTRAsound-Guided PCI in Patients With ST-Elevation Myocardial Infarction

Status unknown Last updated 3 August 2023

What this trial tests

trial testing IVUS imaging for primary PCI guidance in STEMI in 80 participants. Status unknown.

Timeline

1 October 2023

Primary endpoint
1 October 2024

30 December 2025

Quick facts

Lead sponsor	Aristotle University Of Thessaloniki
Status	Status unknown
Study type	OBSERVATIONAL
Enrollment	80
Start date	1 October 2023
Primary completion	1 October 2024
Estimated completion	30 December 2025

Drugs / interventions tested

IVUS imaging for primary PCI guidance

Conditions studied

STEMI — all drugs for STEMI →
Intravascular Imaging — all drugs for Intravascular Imaging →
IVUS — all drugs for IVUS →

Sponsor

Aristotle University Of Thessaloniki

Who can join

18 and older, any sex, with STEMI or Intravascular Imaging. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The main goal of the ULTRA-STEMI trial is to investigate the prognostic impact of IVUS-guided PCI in patients with STEMI and correlate IVUS measurements with clinical, procedural, imaging and follow-up outcomes of interest. Study participants will undergo primary PCI as per standardized procedures; IVUS will be performed at baseline, post-intervention and post-optimization. Manual thrombus aspiration will be performed according to clinical indications. The aspirated thrombi will be collected and scanned with micro-computed tomography (micro-CT). Also, angiographic and peri-procedural data will be gathered. Post-PCI instantaneous wave-free ratio (IFR) will also be performed to assess the severity of the residual coronary-artery stenosis, if any. All patients will be followed up for at least12 months for the adjudication of major adverse cardiovascular events.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Intravascular ULTRA sound-guided percutaneous coronary intervention in patients with STEMI: Rationale and design of the ULTRA-STEMI trial.
Karagiannidis E, Papazoglou AS, Samaras A, Nasoufidou A, et al · · 2025 · PMID 40308625 · DOI 10.4330/wjc.v17.i4.106072

Verify or expand the search:

Other recruiting trials for STEMI

Currently open trials in the same condition.

NCT06966674 — No-Reflow in Patients With STEMI After Intracoronary Tirofiban After Opening of the Track · NA · recruiting
NCT06678074 — Pilot Study of IC14 (Atibuclimab), an Anti-CD14 Monoclonal Antibody, to Treat STEMI · Phase 1, PHASE2 · active not recruiting
NCT07055152 — Retinal OCTA for Microvascular Dysfunction Evaluation and Outcome Prediction in MINOCA Patients · recruiting
NCT06528821 — AI-Powered ECG Detecting Culprit Vessel Blood Flow Abnormality in ACS · active not recruiting
NCT07026708 — TIRANA-ACS: A Prospective Registry Study for the Targeted Investigation of Residual Inflammation After Non-ST/ ST Elevat · recruiting

Other Aristotle University Of Thessaloniki trials

Trials by the same sponsor.

NCT07382479 — NeoAdjuvant ChemoTherapy With KELIM Guided Interval vs. Delayed Interval Debulking Surgery · NA · not yet recruiting
NCT07379905 — MODUCARE Versus Wait-and-See Approach for Histologically Proven Low-grade Cervical Intraepithelial Neoplasia (CIN1) · NA · not yet recruiting
NCT07335016 — The Role of Follicular Flushing at Oocyte Retrieval · NA · not yet recruiting
NCT07297121 — Validation of the Montreal Cognitive Assessment (MoCA) Version 8.x and MoCA-MIS in Greece. · not yet recruiting
NCT07210164 — Pre-habilitation Within ERAS Protocol for Gynecologic Oncology Surgery: The Pre_ERAS Study · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05974930 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Aristotle University Of Thessaloniki
Last refreshed: 3 August 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05974930.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing