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NCT05973357
The Influence of Vertical Implant Position With Immediate Provisionalization on the Marginal Bone Loss.
NA trial testing Sub-crestal implant in Dental Implant Failed in 60 participants. Status unknown.
20 September 2025
Quick facts
| Lead sponsor | Cairo University |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | treatment |
| Enrollment | 60 |
| Start date | 20 September 2023 |
| Primary completion | 20 September 2025 |
| Estimated completion | 30 October 2025 |
Drugs / interventions tested
- Sub-crestal implant
- Equi-crestal implant
Conditions studied
- Dental Implant Failed — all drugs for Dental Implant Failed →
- Implant Site Reaction — all drugs for Implant Site Reaction →
Sponsor
Cairo University
Who can join
Adults 18 to 50, any sex, with Dental Implant Failed or Implant Site Reaction. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Multiple clinical studies have established high survival rates and tremendous predictability of dental implant treatment. However, a pleasant esthetic outcome is the patient's primary expectation regarding implants in the esthetic zone and several esthetic factors have been evaluated to contribute to an esthetic appearance. Among these, the midfacial soft tissue level is considered to be one of the most important factors; Cosyn and co-workers reported that among factors including soft tissue phenotype, the midfacial recession was associated with the position of the implant . Therefore, subcrestal implant placement has been advocated as it has been associated with the reduction of crestal bone loss in cases with decreased soft tissue thickness. If the vertical soft tissues on the crest of the alveolar ridge are 2 mm or less at the time of implant placement, implants will undergo unavoidable bone resorption by establishing sufficient biologic protection. Another option was proposed by Linkevicius et al, who introduced the subcrestal implant placement as a method to accommodate the problem of thin soft tissues. Research question: Does the placement of delayed implants with different vertical depth affect the marginal bone loss with immediate provisionalization?
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT05973357
- Europe PMC full search
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Other Cairo University trials
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05973357 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Cairo University
- Last refreshed: 2 August 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05973357.
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