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NCT05967156
Empagliflozin in Heart Failure Dialysis Patients
NA trial testing Empagliflozin10Mg Tab in Heart Failure in 30 participants. Completed in 3 June 2025.
1 June 2025
Quick facts
| Lead sponsor | Shahid Beheshti University of Medical Sciences |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 30 |
| Start date | 1 June 2023 |
| Primary completion | 1 June 2025 |
| Estimated completion | 3 June 2025 |
| Sites | 1 location across Iran |
Drugs / interventions tested
- Empagliflozin10Mg Tab — full drug profile →
Conditions studied
- Heart Failure — all drugs for Heart Failure →
- Hemodialysis — all drugs for Hemodialysis →
Sponsor
Shahid Beheshti University of Medical Sciences
Who can join
Eligibility, any sex, with Heart Failure or Hemodialysis. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Empagliflozin is not still approved for glomerular filtration rate \< 20 cc/min/1.73m2. Considering the cardiac and renal benefits of this drug, the evaluation of the safety and efficacy of Empagliflozin for heart failure dialysis patients seems to be mandatory.
Publications & conference data
3 peer-reviewed publications reference this trial (live from Europe PMC):
-
Is There a Role for SGLT2 Inhibitors in Patients with End-Stage Kidney Disease?
Siddiqui R, Obi Y, Dossabhoy NR, Shafi T. · · 2024 · cited 15× · PMID 38913113 · DOI 10.1007/s11906-024-01314-3 -
SGLT2 inhibitors in hemodialysis or peritoneal dialysis patients: rationale and state-of-the art.
Minutolo R, Ruotolo C, Conte G, Borrelli S. · · 2026 · cited 2× · PMID 41487902 · DOI 10.1093/ckj/sfaf350 -
The Intertwined Challenge: A Prospective Assessment of Empagliflozin Safety in Hemodialysis-Dependent Patients with Heart Failure
Ahmadi N, Nikmanesh M, Anvari S, heidari S, et al · · 2025 · DOI 10.21203/rs.3.rs-7667019/v1
Verify or expand the search:
- PubMed search for NCT05967156
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Empagliflozin10Mg Tab
Trials testing the same drug.
- NCT07379788 — ARNI Combined With SGLT2 Inhibitors on Functional Mitral Regurgitation Remodeling · recruiting
- NCT04906213 — CardioRenal Effects of SGLT2 Inhibition in Kidney Transplant Recipients · Phase 2 · terminated
Other recruiting trials for Heart Failure
Currently open trials in the same condition.
- NCT06118983 — Improving TRansitions ANd OutcomeS for Heart FailurE Patients in Home Health CaRe (I-TRANSFER-HF) · NA · recruiting
- NCT07496372 — Efficacy and Safety of Human Induced Pluripotent Stem Cell-Derived Cardiomyocyte Injection (HiCM-188) in Advanced Heart · Phase 3 · recruiting
- NCT07527156 — Prolonged Nasogastric Administration of Ketones in Decompensated Heart Failure · Phase 4 · recruiting
- NCT07263035 — Urine Sodium-Driven Diuretic Adjustment Strategy in Acute Decompensated Heart Failure · Phase 4 · recruiting
- NCT07531966 — Vascular Complications After Kidney Transplantation · recruiting
Other Shahid Beheshti University of Medical Sciences trials
Trials by the same sponsor.
- NCT07005687 — Using MSCs for Chronic Active Antibody Mediated Rejection · NA · not yet recruiting
- NCT07435558 — Homogeneous vs. Heterogeneous Learning Style Grouping in Problem-Based Learning Among Nurses · NA · not yet recruiting
- NCT07408492 — Impact of AI-Based Research Training on Nursing Students · NA · not yet recruiting
- NCT07176663 — Efficacy and Safety of Tirzepatide (Spartina) in Chronic Kidney Failure · NA · not yet recruiting
- NCT07291622 — Synchrony-Optimized Non-Invasive Ventilation Education Program and ICU Patients · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05967156 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Shahid Beheshti University of Medical Sciences
- Last refreshed: 6 June 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05967156.
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