NCT05966025 (MAFLD) is a Phase 2 clinical trial of Itopride in Fatty Liver Disease, sponsored by October 6 University.

Who is sponsoring NCT05966025?

NCT05966025 is sponsored by October 6 University.

What drugs are being tested in NCT05966025?

Interventions in NCT05966025: Itopride, conventional therapy.

What condition does NCT05966025 study?

NCT05966025 studies Fatty Liver Disease, Fatty Liver.

Is NCT05966025 still recruiting?

NCT05966025 is currently status unknown. Last updated 28 October 2023.

Last reviewed 2023-10-28 · How we verify

NCT05966025: MAFLD

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Evaluation of the Potential Benefits of Itopride in the Management of Patients With Metabolic Associated Fatty Liver Disease

Status unknown Phase 2 Last updated 28 October 2023

What this trial tests

Phase 2 trial testing Itopride in Fatty Liver Disease in 60 participants. Status unknown.

Timeline

28 December 2023

Primary endpoint
1 December 2024

1 December 2025

Quick facts

Lead sponsor	October 6 University
Phase	Phase 2
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	treatment
Enrollment	60
Start date	28 December 2023
Primary completion	1 December 2024
Estimated completion	1 December 2025
Sites	1 location across Egypt

Drugs / interventions tested

Itopride (ITOPRIDE) — full drug profile →
conventional therapy — full drug profile →

Conditions studied

Fatty Liver Disease — all drugs for Fatty Liver Disease →
Fatty Liver — all drugs for Fatty Liver →

Sponsor

October 6 University

Who can join

Adults 18 to 60, any sex, with Fatty Liver Disease or Fatty Liver. Patients with the condition only — healthy volunteers not accepted.

What's being measured

Primary outcomes are the specific endpoints the trial is designed to prove or disprove.

incidence of MAFLD
Time frame: "1 Year "
Highly sensitive CRP in mg\\L by ELIZA, Fibro scan in MHzby fibroscan apparatus, ALT,AST in unit\\liter by blood test

Sponsor's own description

Objective of this study is to determine the clinical benefits of itopride in improvement of MAFLD

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

Verify or expand the search:

Other trials of Itopride

Trials testing the same drug.

NCT04104867 — Effectiveness of Prokinetic Agents in Improving Abdominal Discomfort at Colonoscopy · NA · unknown
NCT04161768 — Norfloxacin With Itopride Versus Norfloxacin in Secondary Prophylaxis of Spontaneous Bacterial Peritonitis · Phase 3 · recruiting
NCT04697641 — Helicobacter Pylori Eradication in Functional Dyspepsia · NA · completed

Other recruiting trials for Fatty Liver Disease

Currently open trials in the same condition.

NCT07214870 — A Research Study of a Potential New Medicine (NNC4005-0001) for Liver Disease in Adult Participants With Increased Body · Phase 1 · recruiting
NCT06302049 — Clinical Study Evaluating the Safety and Efficacy of Esomeprazole in Treatment of Non-alcoholic Steatohepatitis · Phase 1, PHASE2 · recruiting
NCT06585982 — Synbiotics Impact on Insulin and TNF-α in MAFLD: a Gut Microbiota Profile Analysis · NA · recruiting
NCT06802731 — LivQ-box® Parameters in the Diagnosis of Liver Inflammation · recruiting
NCT06720766 — Assessment of FibbroScan in Diagnosing MASLD Among the Chinese Population With Obesity · recruiting

Other October 6 University trials

Trials by the same sponsor.

NCT07235072 — Passive Fit and Time Efficiency in All On-X Implants Protocols Using Photogrammetry, Splinted Scan Bodies, and Conventio · NA · not yet recruiting
NCT07403851 — Effect of Scanning Technology on the Accuracy of Digitally Customized Intraradicular Attachments · NA · not yet recruiting
NCT07305792 — High Tone Power Therapy on Lumbosacral Radiculopathy Patients · NA · completed
NCT07132736 — Impact of Underwater Exercise Versus Regular Aerobic Exercise on Quality of Life and Power of Muscle · NA · recruiting
NCT07350655 — Efficacy of Virtual Reality-based Training in Patients With Chronic Non-specific Low Back Pain · NA · active not recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05966025 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by October 6 University
Last refreshed: 28 October 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05966025.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing