Last reviewed · How we verify

NCT05961410: EPBSCH

Eltrombopag for Peripheral Blood Stem Cell Harvest

Recruiting now Phase 2 Last updated 18 October 2024
What this trial tests

Phase 2 trial testing Eltrombopag olamine in Lymphoma in 46 participants. Currently enrolling.

Timeline
15 August 2023
Primary endpoint
31 March 2025
1 March 2026

Quick facts

Lead sponsorNational Taiwan University Hospital
PhasePhase 2
StatusRecruiting now
Study typeINTERVENTIONAL
Allocationna
Designsingle group
Maskingnone
Primary purposetreatment
Enrollment46
Start date15 August 2023
Primary completion31 March 2025
Estimated completion1 March 2026
Sites1 location across Taiwan

Drugs / interventions tested

Conditions studied

Sponsor

National Taiwan University Hospital

Who can join

18 and older, any sex, with Lymphoma or Peripheral Blood Stem Cell Transplantation. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The goal of this clinical trial is to explore the activity of eltrombopag in lymphoma patients receiving autologous hematopoietic stem cell harvest. The main questions it aims to answer are: * Determine the efficacy of adding eltrombopag during autologous hematopoietic stem cell mobilization and harvest. * Determine the pharmacokinetics and pharmacodynamics of serum eltrombopag concentration, circulating CD34+ cells during autologous hematopoietic stem cell mobilization. Participants will receiving additional eltrombopag during stem cell harvest procedure. The amount of harvested stem cells will be compared with historical group to see if eltrombopag could increase the amount of harvested stem cells.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. RNA m6A modification in ferroptosis: implications for advancing tumor immunotherapy.
    Shi JX, Zhang ZC, Yin HZ, Piao XJ, et al · · 2024 · cited 29× · PMID 39342168 · DOI 10.1186/s12943-024-02132-6

Verify or expand the search:

Other recruiting trials for Lymphoma

Currently open trials in the same condition.

Other National Taiwan University Hospital trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05961410.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing