NCT05958966

Effects of e-Cigarettes on Perceptions and Behavior - Substudy 2

Completed NA Last updated 25 July 2023

What this trial tests

NA trial testing E-cigarette e-liquid self-administration in Electronic Cigarette Use in 73 participants. Completed in 1 May 2023.

Timeline

1 April 2022

Primary endpoint
1 May 2023

1 May 2023

Quick facts

Lead sponsor	University of Southern California
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	factorial
Masking	double
Primary purpose	other
Enrollment	73
Start date	1 April 2022
Primary completion	1 May 2023
Estimated completion	1 May 2023
Sites	1 location across United States

Drugs / interventions tested

• E-cigarette e-liquid self-administration

Conditions studied

• Electronic Cigarette Use — all drugs for Electronic Cigarette Use →
• E-Cig Use — all drugs for E-Cig Use →
• Cigarette Smoking — all drugs for Cigarette Smoking →
• Cigarette Use, Electronic — all drugs for Cigarette Use, Electronic →

Sponsor

University of Southern California

Who can join

21 and older, any sex, with Electronic Cigarette Use or E-Cig Use. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This project will assess the ways in which e-cigarette product diversity impacts the user experience to inform potential regulations by identifying product characteristics that may: (1) put young adults at risk for tobacco product use; and (2) facilitate adult smokers switching to e-cigarettes. There are three primary objectives to the study: (1) Determine which dimensions of e-cigarette product diversity differentially affect product appeal in the overall population of tobacco product users as well as affect product appeal across young adult e-cigarette users and middle-age/older adult smokers; (2) Determine which dimensions of e-cigarette product diversity differentially affect product appeal in the overall population of tobacco product users as well as affect abuse liability in young adult e-cigarette users and the ability to resist smoking in adult smokers; (3) Determine the affect of product characteristics on e-cigarette nicotine delivery profile. For this substudy, adult smokers (N=200) will attend two laboratory session in which they will self-administer e-cigarette products varied according to within-subject e-cigarette factors (e.g., flavor, nicotine formulation) and smoke their own cigarettes.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.