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NCT05957835
The Effect of Beetroot Juice Supplementation Dose on Neuromuscular Performance During Resistance Exercise
NA trial testing BR-HIGH in High Nitrate Dose in 18 participants. Status unknown.
28 April 2024
Quick facts
| Lead sponsor | Pepperdine University |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | crossover |
| Masking | double |
| Primary purpose | basic science |
| Enrollment | 18 |
| Start date | 23 May 2023 |
| Primary completion | 28 April 2024 |
| Estimated completion | 30 June 2024 |
| Sites | 1 location across United States |
Drugs / interventions tested
- BR-HIGH
- BR-MOD
- BR-LOW
- PL
Conditions studied
- High Nitrate Dose — all drugs for High Nitrate Dose →
- Moderate Nitrate Dose — all drugs for Moderate Nitrate Dose →
- Low Nitrate Dose — all drugs for Low Nitrate Dose →
- Nitrate-depleted Dose — all drugs for Nitrate-depleted Dose →
Sponsor
Pepperdine University
Who can join
Adults 18 to 45, male only, with High Nitrate Dose or Moderate Nitrate Dose. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Dietary nitrate supplementation, administered in the form of nitrate-rich beetroot juice, has been shown to improve exercise performance and may have more pronounced effects on exercise that requires high-power and high-velocity muscle contraction such as weightlifting and body-mass resisted exercise (i.e, resistance exercise). However, limited data are available that have examined the potential performance enhancing effect of beetroot juice in resistance exercise. Moreover, there is no information on the dose of nitrate required for performance enhancing effects during resistance exercise which limits its widespread use to enhance performance. Therefore, the investigators will assess if supplementing the diet with nitrate-rich beetroot juice impacts resistance exercise performance (e.g., power, velocity), when compared to supplementing the diet with nitrate-depleted beetroot juice (i.e. placebo). The investigators will also investigate the dose-response effect of beetroot juice on resistance exercise performance by providing a low, moderate, and high nitrate dose of concentrated beetroot juice. The results of this study will improve understanding of whether beetroot juice influences resistance exercise performance and will provide insight on whether different doses of beetroot juice influence the efficacy of nitrate supplementation on resistance exercise performance. Together, these data will guide supplementation strategies for enhancing resistance exercise performance.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05957835 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Pepperdine University
- Last refreshed: 24 July 2023
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