NCT05955222 is a NA clinical trial of PEEK in TMD, sponsored by Istanbul University.

Who is sponsoring NCT05955222?

NCT05955222 is sponsored by Istanbul University.

What drugs are being tested in NCT05955222?

Interventions in NCT05955222: PEEK, PMMA, Traditional.

Is NCT05955222 still recruiting?

NCT05955222 is currently completed. Last updated 15 August 2023.

Last reviewed 2023-08-15 · How we verify

NCT05955222

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Clinical Performance of CAD/CAM Splint Materials

Completed NA Last updated 15 August 2023

What this trial tests

NA trial testing PEEK in TMD in 24 participants. Completed in 1 April 2023.

Timeline

2 February 2020

Primary endpoint
30 August 2022

1 April 2023

Quick facts

Lead sponsor	Istanbul University
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	treatment
Enrollment	24
Start date	2 February 2020
Primary completion	30 August 2022
Estimated completion	1 April 2023
Sites	1 location across Turkey (Türkiye)

Drugs / interventions tested

PEEK
PMMA — full drug profile →
Traditional

Conditions studied

TMD — all drugs for TMD →

Sponsor

Istanbul University

Who can join

Adults 18 to 65, any sex, with TMD. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The goal of this clinical study is to compare the performance of computer aided designed and computer aided manufactured (CAD/CAM) occlusal splints with splints produced with conventional methods. The main questions this clinical study aims to answer are: * Do CAD/CAM splints have the same therapeutic effect as the traditional splints ? * Do CAD/CAM splints demonstrate better surface wear and fit and lower wear in opposing jaw than traditional splints ? * Is objective pain evaluation of the patient better with CAD/CAM splints ? Participants were asked to use the splints for 6 months, 8 hours a day and come for follow-up appointments 3 times during this 6 month period: * Delivery appointment * First appointment: one week later after delivery appointment * Last appointment: 6 months after delivery appointment Researchers compared CAD/CAM groups with traditional group to see the clinical performance of the CAD/CAM groups.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

Other trials of PEEK

Trials testing the same drug.

NCT06846632 — Graftless Technique in Open Maxillary Sinus Lifting Using PEEK Versus Ti -Meshwork · NA · completed
NCT03462862 — Evaluation of Candida Albicans Growth on BreFlex Versus PEEK Denture Base in Maxillary Bounded Partial Denture · NA · unknown
NCT03491306 — Evaluation of Microbial Growth on Bre-Flex Versus PEEK Denture Base in Bilateral Maxillary Bounded Partial Denture · NA · unknown
NCT03063008 — Transforaminal Lumbar Interbody Fusion in PEEK Oblique Cages With and Without Titanium Coating · NA · completed

Other recruiting trials for TMD

Currently open trials in the same condition.

NCT07304557 — Effects Exercises in Temporomandibular Joint Disorders on Pain, Joint and Tongue Functions · NA · recruiting
NCT06948162 — Exploration of the Utility of Dental-dedicated MRI for Dentistry · recruiting
NCT07351812 — Two Treatment Modalities for Myogenous Temporomandibular Disorders · NA · recruiting

Other Istanbul University trials

Trials by the same sponsor.

NCT07472946 — Whole-Body Vibration Exercise in Patients With Parkinson's Disease · NA · not yet recruiting
NCT07433894 — Scoliosis and Functional Outcomes in Children With Juvenile Idiopathic Arthritis · not yet recruiting
NCT07420049 — Turkish Adaptation of the CTS-6 Evaluation Tool: A Validation and Reliability Study · not yet recruiting
NCT07415967 — The Effect of a Dual-Task Technique-Based Exercise Program on Clinical Outcomes in Rotator Cuff Related Shoulder Pain · NA · recruiting
NCT07473024 — pEEG-Guided Anesthesia and Behavioral Outcomes in Children · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05955222 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Istanbul University
Last refreshed: 15 August 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05955222.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing