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NCT05951413
The Effect of Sildenafil Citrate on Frozen Embryo Transfer Cycles
Phase 2, PHASE3 trial testing Sildenafil Citrate in IVF in 110 participants. Status unknown.
30 September 2023
Quick facts
| Lead sponsor | Beni-Suef University |
|---|---|
| Phase | Phase 2, PHASE3 |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 110 |
| Start date | 30 June 2023 |
| Primary completion | 30 September 2023 |
| Estimated completion | 30 September 2023 |
| Sites | 1 location across Egypt |
Drugs / interventions tested
- Sildenafil Citrate (Sildenafil Citrate) — full drug profile →
- estradiol (ESTRADIOL) — full drug profile →
Conditions studied
- IVF — all drugs for IVF →
Sponsor
Beni-Suef University
Who can join
Adults 20 to 40, female only, with IVF. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
to investigate the value of adding sildenafil citrate during endometrial preparation in patients undergoing frozen-thawed embryo transfer and its effect on endometrial thickness and pregnancy rates.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Vasodilators for women undergoing fertility treatment.
Gutarra-Vilchez RB, Vazquez JC, Glujovsky D, Lizaraso F, et al · · 2025 · cited 2× · PMID 40047216 · DOI 10.1002/14651858.cd010001.pub4
Verify or expand the search:
- PubMed search for NCT05951413
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Sildenafil Citrate
Trials testing the same drug.
- NCT06178523 — Cost-effective Treatment of Unexplained Infertility · Phase 4 · completed
- NCT05846906 — Effect of Oral Sildenafil Citrate on Improvement of Endometrial Thickness · Phase 2, PHASE3 · completed
- NCT04283435 — Endometrial Effects of Sildenafil in Frozen-Thawed Cycles in Women With Thin Endometrium · Phase 1 · unknown
- NCT04565925 — Sildenafil for Treatment of Urinary Incontinence in Patients With Spinal Cord Injuries · Phase 2 · recruiting
- NCT04898114 — Nebulized Magnesium Sulfate and Sildenafil for Persistent Pulmonary Hypertension of Newborn · Phase 1, PHASE2 · recruiting
Other recruiting trials for IVF
Currently open trials in the same condition.
- NCT07364526 — Non-Invasive Preimplantation Genetic Screening for Aneuploidies and Clinical Outcomes in Egg Donation Patients · recruiting
- NCT07088640 — Single Step Protocol and Multi-step Warming Protocol for Blastocyst FET · NA · recruiting
- NCT06544837 — Trial to Evaluate the Clinical Utility of Non-invasive Endometrial Receptivity Test (Ora) in Patients With Implantation · NA · recruiting
- NCT06334003 — Cardiometabolic Function in Offspring, Mother and Placenta After Assisted Reproductive Technology · recruiting
- NCT06577181 — Effect of HCG on Endometrial Preparation in Frozen Embryo Transfer · active not recruiting
Other Beni-Suef University trials
Trials by the same sponsor.
- NCT07536347 — Effect of Adding PNF to IMT on Weaning Off MV · NA · not yet recruiting
- NCT07494240 — Effects of Changes in Driving Pressure on Intraoperative Pulmonary Dynamic Compliance and PaO₂/FiO₂ Ratio in Laparoscopi · NA · not yet recruiting
- NCT07506499 — Cardiac Rehabilitation in Decompensated Heart Failure · NA · recruiting
- NCT07482631 — Robotic Glove Training on Hand Function in Unilateral Cerebral Palsy · NA · not yet recruiting
- NCT07509736 — Effect of Pulmonary Rehabilitation in Females With Acute Exacerbation of COPD Induced by Biomass Fuel Smoke · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05951413 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Beni-Suef University
- Last refreshed: 19 July 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05951413.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing