NCT05950035 is a NA clinical trial of Written Exposure Therapy (WET) in Posttraumatic Stress Disorder, sponsored by Palo Alto Veterans Institute for Research.

Who is sponsoring NCT05950035?

NCT05950035 is sponsored by Palo Alto Veterans Institute for Research.

What condition does NCT05950035 study?

NCT05950035 studies Posttraumatic Stress Disorder, Insomnia, Nightmare.

Is NCT05950035 still recruiting?

NCT05950035 is currently completed. Last updated 31 May 2025.

Last reviewed 2025-05-31 · How we verify

NCT05950035

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

An Efficient Treatment for Posttraumatic Injury for Firefighters

Completed NA Last updated 31 May 2025

What this trial tests

NA trial testing Written Exposure Therapy (WET) in Posttraumatic Stress Disorder in 49 participants. Completed in 1 January 2025.

Timeline

1 December 2023

Primary endpoint
1 January 2025

1 January 2025

Quick facts

Lead sponsor	Palo Alto Veterans Institute for Research
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	treatment
Enrollment	49
Start date	1 December 2023
Primary completion	1 January 2025
Estimated completion	1 January 2025
Sites	1 location across United States

Drugs / interventions tested

Written Exposure Therapy (WET)
Cognitive Behavioral Therapy for Insomnia (CBTi)
Cognitive Behavioral Therapy for Nightmares (CBTn)
Waitlist

Conditions studied

Posttraumatic Stress Disorder — all drugs for Posttraumatic Stress Disorder →
Insomnia — all drugs for Insomnia →
Nightmare — all drugs for Nightmare →

Sponsor

Palo Alto Veterans Institute for Research

Who can join

Adults 18 to 65, any sex, with Posttraumatic Stress Disorder or Insomnia. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The goal of this two-arm pilot randomized controlled trial is to test a behavioral intervention that integrates three evidence-based cognitive behavioral interventions (written exposure therapy; WET, cognitive behavioral therapy for insomnia; CBT-I, and cognitive behavioral therapy for nightmares; CBT-N) among firefighters. The main questions it aims to answer are: * Is the behavioral intervention feasible, acceptable, and effective in reducing symptoms of posttraumatic stress, insomnia, and nightmares? * What is the efficacy of efficient treatment vs. delayed treatment (2-4 week waitlist) in reducing symptoms of posttraumatic stress, insomnia, and nightmares? We will beta test the intervention in 1-2 groups of 3-5 firefighters. Then we will randomize 50 participants to immediate or delayed (2-4 week waitlist) treatment. Consented participants will: * Complete self-report and interview measures assessing posttraumatic stress disorder, insomnia (PTSD), and nightmares * Attend an individual treatment orientation session * Attend a 4-day (\~3 hours per day over 4 consecutive days) group treatment that integrates WET, CBT-I, and CBT-N * Attend an individual booster session held approximately one week later * Complete self-report measures before, during, and after treatment, and at a 3-month follow up assessment and a clinical interview before and after treatment to assess program efficacy.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

Other trials of Written Exposure Therapy (WET)

Trials testing the same drug.

NCT07069517 — Accelerated Treatment for Co-occurring Insomnia, Nightmares, and PTSD · NA · recruiting
NCT05486793 — Treatment for Antepartum Posttraumatic Stress Disorder/PTSD Study · NA · recruiting
NCT05419999 — Transcranial Direct Current Stimulation (tDCS) in Human Subjects With PTSD Receiving an Exposure-based, Behavioral Thera · NA · completed

Other Palo Alto Veterans Institute for Research trials

Trials by the same sponsor.

NCT07219251 — Engagement of Veterans With Lung Cancer · NA · recruiting
NCT06704061 — Online Yoga vs Acceptance and Commitment Therapy for Treating Chronic Musculoskeletal Pain · NA · recruiting
NCT07069517 — Accelerated Treatment for Co-occurring Insomnia, Nightmares, and PTSD · NA · recruiting
NCT07303725 — Intra-procedural Spectral CT for Image-guided Embolization and Ablation in Interventional Oncology · recruiting
NCT07303712 — Liquid Biopsy for Hepatocellular Carcinoma Molecular Characterization After Y90 · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05950035 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Palo Alto Veterans Institute for Research
Last refreshed: 31 May 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05950035.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing