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NCT05947318: tACS
Effect of tACS on the Recovery of Motor Control of the Upper Limb and Cerebral Connectivity in Chronic Stroke Patients
NA trial testing transcranial alternating current stimulation 70 Hz in Chronic Stroke in 59 participants. Completed in 7 April 2025.
7 April 2025
Quick facts
| Lead sponsor | Universidad Metropolitana de Ciencias de la Educacion |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | single group |
| Masking | triple |
| Primary purpose | treatment |
| Enrollment | 59 |
| Start date | 2 May 2023 |
| Primary completion | 7 April 2025 |
| Estimated completion | 7 April 2025 |
| Sites | 1 location across Chile |
Drugs / interventions tested
- transcranial alternating current stimulation 70 Hz
- Training
- transcranial alternating current stimulation 7 Hz
- transcranial alternating current stimulation Sham
Conditions studied
- Chronic Stroke — all drugs for Chronic Stroke →
- Rehabilitation — all drugs for Rehabilitation →
Sponsor
Universidad Metropolitana de Ciencias de la Educacion
Who can join
Adults 18 to 80, any sex, with Chronic Stroke or Rehabilitation. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This project seeks to evaluate the effect of transcranial alternating current stimulation (tACS) on the recovery of motor control of the upper limb and associated neuronal synchrony during a 14-sessions (5-week) rehabilitation program for adult patients with diagnosis of stroke at chronic stage. Specifically, the stimulation on Gamma ranges, because the evidence available so far allows us to propose that the tACS in the Gamma range (around 70 Hz) facilitates motor execution. For this purpose, the experimental approach involves active (70 Hz in Gamma rhythm and 7 Hz, Theta rhythm) and sham tACS together with an analytical and integrated motor training with a double-blind and randomized design. Our hypothesis is that Gamma frequency tACS restores neuronal synchrony in Beta range, which enhances the upper limb motor recovery associated with a training program. Using specific motor control parameters, clinical scales and electroencephalography, the immediate and long-term (3 months after finished the training) behavioral and neurophysiological effect of this new neurostimulation paradigm (tACS plus training) for motor rehabilitation of stroke will be established.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT05947318
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Chronic Stroke
Currently open trials in the same condition.
- NCT07468110 — Evaluation Of The Relationship Between The Conut Score And Balance And Functional Status In Patients With Chronic Stroke · recruiting
- NCT07378774 — Constraint Induced Movement Therapy and Bilateral Training in Chronic Stroke · NA · recruiting
- NCT07353203 — Safety and Efficacy of Hip Assist Powered Exoskeleton for Gait Training in Patients With Late Subacute and Chronic Strok · NA · recruiting
- NCT07065292 — Plantar Sensation, Position Sense, and Weight-Bearing Asymmetry Related to Balance and Mobility Post-Stroke · recruiting
- NCT06286800 — Personalized Transcranial Direct Current Stimulation in Stroke Recovery · NA · recruiting
Other Universidad Metropolitana de Ciencias de la Educacion trials
Trials by the same sponsor.
- NCT06846918 — HIIT Vs Snack Exercises on the Academic Stress of University Students · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05947318 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Universidad Metropolitana de Ciencias de la Educacion
- Last refreshed: 29 April 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05947318.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing