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China Antihypertensive Trial for Intracranial Aneurysm (ChATIA-1)
The goal of this randomized controlled trial is to evaluate the benefits and safety of controlled hypotension in Chinese patients with unruptured intracranial aneurysms(UIA). The main questions it aims to answer are: * To provide high-level evidence of the benefits and safety of controlled hypotension in patients with UIA. * To provide evidence-based medical evidence for blood pressure control of patients with UIA in neurosurgery, and promote the progress of accurate individual management of patients. In this study, the main intervention is enhanced blood pressure lowering in patients with UIA. All Patients will be randomly assigned to either the standard blood pressure lowering (SBPL) group or the enhanced blood pressure lowering (EBPL) group.
Details
| Lead sponsor | Beijing Tiantan Hospital |
|---|---|
| Phase | NA |
| Status | COMPLETED |
| Enrolment | 577 |
| Start date | Sat Jul 01 2023 00:00:00 GMT+0000 (Coordinated Universal Time) |
| Completion | Mon Jan 19 2026 00:00:00 GMT+0000 (Coordinated Universal Time) |
Conditions
- Unruptured Intracranial Aneurysm
Interventions
- blood pressure lowering
Countries
China