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NCT05938283: HICD
Pilot Study of Hypertrophic Cardiomyopathy & Implantable Cardioverter Defibrillator Assessment: (Subcutaneous vs Transvenous)
NA trial testing Implantable Cardioverter Defibrillator implant in Implantable Defibrillator User in 5 participants. Completed in 7 January 2026.
7 January 2026
Quick facts
| Lead sponsor | Barts & The London NHS Trust |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 5 |
| Start date | 10 January 2024 |
| Primary completion | 7 January 2026 |
| Estimated completion | 7 January 2026 |
| Sites | 1 location across United Kingdom |
Drugs / interventions tested
- Implantable Cardioverter Defibrillator implant
Conditions studied
- Implantable Defibrillator User — all drugs for Implantable Defibrillator User →
- Hypertrophic Cardiomyopathy — all drugs for Hypertrophic Cardiomyopathy →
- Implantable Cardioverter Ventricular Lead Dysfunction or Complication — all drugs for Implantable Cardioverter Ventricular Lead Dysfunction or Complication →
- Ventricular Arrythmia — all drugs for Ventricular Arrythmia →
Sponsor
Barts & The London NHS Trust — full company profile →
Who can join
18 and older, any sex, with Implantable Defibrillator User or Hypertrophic Cardiomyopathy. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Pilot randomised trial to assess recruitment for a larger trial to compare the efficacy and adverse effects of the subcutaneous and transvenous ICD in patients with hypertrophic cardiomyopathy (HCM) and indication for ICD therapy, with no requirement for pacing
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT05938283
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Implantable Defibrillator User
Currently open trials in the same condition.
- NCT03544489 — Effectiveness of Exercise After an ICD · Phase 2, PHASE3 · recruiting
- NCT06937658 — Remote Alert Pathway To Optimize CaRe of Cardiac Implantable Electrical Devices · NA · recruiting
- NCT06388382 — Investigation of the Audible ICD Alert Tone · recruiting
- NCT06037785 — Self-Management Interventions After an ICD Shock · NA · recruiting
- NCT05835791 — END - VT Cohort Study · recruiting
Other Barts & The London NHS Trust trials
Trials by the same sponsor.
- NCT05753085 — Multimodality Optical and Ultrasound Intravascular Imaging for Stent Optimization and Atheroma Assessment · NA · withdrawn
- NCT07047235 — Substrate Remodelling and Targeted Ablation in AF · NA · recruiting
- NCT06871215 — Inflammation and Infective Endocarditis · withdrawn
- NCT07076524 — MuScle WastIng and DysphaGia iN CriticAlly IlL Patients (SIGNAL) · recruiting
- NCT06596486 — A Comparison of CoolStick With Ethyl Chloride for the Assessment of Light Touch · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05938283 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Barts & The London NHS Trust
- Last refreshed: 19 February 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05938283.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing