NCT05938140 (ESPTCSCKD) is a Phase 4 clinical trial of Nirmatrelvir/ritonavir in COVID-19, sponsored by Chinese PLA General Hospital.

Who is sponsoring NCT05938140?

NCT05938140 is sponsored by Chinese PLA General Hospital.

What drugs are being tested in NCT05938140?

Interventions in NCT05938140: Nirmatrelvir/ritonavir.

What condition does NCT05938140 study?

NCT05938140 studies COVID-19, Renal Insufficiency, Chronic.

Is NCT05938140 still recruiting?

NCT05938140 is currently status unknown. Last updated 10 July 2023.

Last reviewed 2023-07-10 · How we verify

NCT05938140: ESPTCSCKD

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Efficiency and Safety of Paxlovid for COVID-19 Patients With Severe Chronic Kidney Disease

Status unknown Phase 4 Last updated 10 July 2023

What this trial tests

Phase 4 trial testing Nirmatrelvir/ritonavir in COVID-19 in 30 participants. Status unknown.

Timeline

22 June 2023

Primary endpoint
30 May 2025

30 May 2025

Quick facts

Lead sponsor	Chinese PLA General Hospital
Phase	Phase 4
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	treatment
Enrollment	30
Start date	22 June 2023
Primary completion	30 May 2025
Estimated completion	30 May 2025
Sites	1 location across China

Drugs / interventions tested

Nirmatrelvir/ritonavir

Conditions studied

COVID-19 — all drugs for COVID-19 →
Renal Insufficiency, Chronic — all drugs for Renal Insufficiency, Chronic →

Sponsor

Chinese PLA General Hospital

Who can join

18 and older, any sex, with COVID-19 or Renal Insufficiency, Chronic. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This is a prospective, single-center, open and self-controlled study.The purpose of this study is to evaluate the efficacy and safety of Paxlovid for the treatment of COVID-19 patients with severe chronic kidney disease.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

Verify or expand the search:

Other trials of Nirmatrelvir/ritonavir

Trials testing the same drug.

NCT06397144 — A Study on 2 Different Combination Tablets of Nirmatrelvir Plus Ritonavir to Compare Them With Marketed Paxlovid in Heal · Phase 1 · withdrawn
NCT05898672 — A Study to Learn About the Study Medicine Called Nirmatrelvir/Ritonavir in People Who Are Healthy Volunteers Co-administ · Phase 1 · completed
NCT05852873 — PAxlovid loNg cOvid-19 pRevention triAl With recruitMent In the Community in Norway · Phase 3 · active not recruiting
NCT05823896 — ImPROving Quality of LIFe in the Long COVID Patient · Phase 2 · completed
NCT05690646 — Prophylactic Effect of Nirmatrelvir/Ritonavir and Ursodeoxycholic Acid on Reducing Complications After Cardiac Surgery · Phase 4 · unknown

Other recruiting trials for COVID-19

Currently open trials in the same condition.

NCT07183709 — Safety and Immunogenicity Trial of PepGNP-COVID19 Vaccine in Adults · Phase 1 · active not recruiting
NCT07300839 — A Study to Learn About a COVID-19 Vaccine in Healthy Adults 50 Through 64 Years of Age · Phase 3 · active not recruiting
NCT07221162 — A Safety and Immunogenicity Trial of Boost-2867 Vaccine, Via Intranasal and Intramuscular Routes · Phase 1 · recruiting
NCT07215520 — Safety and Tolerability of a Newcastle Disease Virus-Based Mucosal COVID-19 Vaccine in Previously Vaccinated Adults · Phase 2 · recruiting
NCT07222384 — A Study to Learn About BNT162b2 (LP.8.1)-Adapted Vaccine Against SARS-CoV-2 in Children 5 Through 11 Years of Age That A · Phase 3 · active not recruiting

Other Chinese PLA General Hospital trials

Trials by the same sponsor.

NCT07294755 — The Impact of Intrapleural Block on Postoperative Pain Caused by Drainage Tubes After Thoracoscopic Surgery · NA · not yet recruiting
NCT07536607 — Predictive Role of Photon Counting Computed Tomography in Acute Coronary Syndrom Patients · not yet recruiting
NCT07489157 — Real-Time End-Tidal Carbon Dioxide Monitoring for Early Warning of Hypoxemia in Painless Gastrointestinal Endoscopy · NA · not yet recruiting
NCT07494981 — Individualized Precision Therapy With Ceftazidime and Avibactam Guided by PK/PD in Geriatric Populations · not yet recruiting
NCT07496008 — Individualized Precision Isavuconazole Therapy Guided by PK/PD Principles for the Geriatric Population · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05938140 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Chinese PLA General Hospital
Last refreshed: 10 July 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05938140.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing